Bepotastine Ophthalmic

Name: Bepotastine Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

7 interactions 20 cited references

Also sold as: Bepreve Bepreve®

About Bepotastine Ophthalmic

Bepotastine ophthalmic is used to treat itching of the eyes caused by allergic conjunctivitis (a condition in which the eyes become itchy, swollen, red, and teary when they are exposed to certain substances in the air). Bepotastine is in a class of medications called antihistamines. It works by blocking the action and… Read the full Bepotastine Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amifampridine Bupropion Clomipramine Donepezil Hydroxychloroquine Pitolisant

7 Major

All (7) Major (7)

Major

Bepotastine Ophthalmic Amifampridine Increased risk of seizures Details Bepotastine Ophthalmic Bupropion Aplenzin Increased risk of seizures Details Bepotastine Ophthalmic Clomipramine Anafranil Increased risk of seizures Details Bepotastine Ophthalmic Donepezil Adlarity Reduced seizure threshold Details Bepotastine Ophthalmic Hydroxychloroquine Plaquenil An increased risk of seizures Details Bepotastine Ophthalmic Pitolisant Wakix Reduced efficacy of pitolisant Details Bepotastine Ophthalmic Tramadol ConZip An increased risk of seizure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.