Sulpiride

82 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Nasal Spray Cabergoline Metoclopramide Injection Levodopa Oral Inhalation Oxaliplatin Injection Cetirizine Ophthalmic
4 Contraindicated 77 Major 1 Moderate
All (82) Contraindicated (4) Major (77) Moderate (1)

Contraindicated

Sulpiride Cabergoline Dostinex® Decreased efficacy of either drug Details Sulpiride Levodopa Oral Inhalation Inbrija Decreased efficacy of either drug Details Sulpiride Metoclopramide Injection Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Sulpiride Metoclopramide Nasal Spray Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

Major

Sulpiride Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Sulpiride Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Sulpiride Sertraline Explained An increased risk of QT interval prolongation Details Sulpiride Buprenorphine Belbuca Explained An increased risk of QT interval prolongation and an increased risk of CNS and respiratory depression Details Sulpiride Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Sulpiride Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Sulpiride Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Sulpiride Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Sulpiride Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Sulpiride Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation Details Sulpiride Azithromycin AzaSite An increased risk of QT interval prolongation Details Sulpiride Alfuzosin UroXatral An increased risk of QT interval prolongation Details Sulpiride Anagrelide Agrylin An increased risk of QT interval prolongation Details Sulpiride Bedaquiline Sirturo An increased risk of QT interval prolongation Details Sulpiride Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Sulpiride Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Sulpiride Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Sulpiride Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Sulpiride Chloroquine Aralen® An increased risk of QT interval prolongation Details Sulpiride Dasatinib Phyrago An increased risk of QT interval prolongation Details Sulpiride Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Sulpiride Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Sulpiride Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Sulpiride Diazepam Rectal Diastat Increased risk of CNS depression Details Sulpiride Disopyramide Norpace An increased risk of QT interval prolongation Details Sulpiride Dofetilide Tikosyn An increased risk of QT interval prolongation Details Sulpiride Dolasetron Anzemet An increased risk of QT interval prolongation Details Sulpiride Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Sulpiride Encorafenib Braftovi Increased risk of QT interval prolongation Details Sulpiride Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Sulpiride Eribulin Injection Halaven An increased risk of QT interval prolongation Details Sulpiride Esketamine Nasal Spray Spravato Increased risk of sedation Details Sulpiride Famotidine Calmicid An increased risk of QT interval prolongation Details Sulpiride Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Sulpiride Felbamate Felbatol An increased risk of QT interval prolongation Details Sulpiride Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.