Ambrisentan
11 interactions 37 cited referencesAmbrisentan is used alone or in combination with tadalafil (Adcirca, Cialis) to treat pulmonary arterial hypertension (PAH, high blood pressure in the vessels that carry blood to the lungs). Ambrisentan may improve the ability to exercise and slow the worsening of symptoms in people with PAH. Ambrisentan is in a class… Read the full Ambrisentan drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Ambrisentan Azathioprine Azasan An increased risk of hepatotoxicity Details Ambrisentan Cyclosporine Atopica Increased ambrisentan exposure Details Ambrisentan Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Ambrisentan Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Ambrisentan Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Ambrisentan Simeprevir Olysio® Increased exposure of P-gp substrate Details Ambrisentan Cyclosporine Injection Atopica Increased ambrisentan exposure Details Ambrisentan Cyclosporine Ophthalmic Cequa Increased ambrisentan exposure Details Ambrisentan Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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