Dorzolamide Ophthalmic

Name: Dorzolamide Ophthalmic Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions 162 cited references

Also sold as: Trusopt® Ocumeter® Plus

About Dorzolamide Ophthalmic

Ophthalmic dorzolamide is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Dorzolamide is in a class of medications called carbonic anhydrase inhibitors. It works by decreasing the pressure in the eye. Read the full Dorzolamide Ophthalmic drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Memantine Metformin Topiramate

4 Major

All (4) Major (4)

Major

Dorzolamide Ophthalmic Aspirin Acuprin® Increased carbonic anhydrase inhibitors exposure and its toxicity Details Dorzolamide Ophthalmic Memantine Namenda Reduced clearance of memantine Details Dorzolamide Ophthalmic Metformin Fortamet® An increased risk of lactic acidosis and reduced serum bicarbonate Details Dorzolamide Ophthalmic Topiramate Eprontia An increased risk of nephrolithiasis and severity of metabolic acidosis Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.