Carbidopa

24 interactions 2 explained in plain English
Also sold as: Lodosyn
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Linezolid Injection Acetaminophen And Codeine Diphenhydramine Injection Morphine Injection Butorphanol Injection Butorphanol Nasal Spray
1 Contraindicated 22 Major 1 Moderate
All (24) Contraindicated (1) Major (22) Moderate (1)

Contraindicated

Carbidopa Linezolid Injection Zyvox Hypertensive crisis Details

Major

Carbidopa Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of CNS depression Details Carbidopa Buprenorphine Belbuca Explained An increased risk of CNS depression Details Carbidopa Aripiprazole Injection Abilify An increased risk of CNS depression Details Carbidopa Asenapine Transdermal Patch Secuado An increased risk of CNS depression Details Carbidopa Butorphanol Injection Butorphic An increased risk of CNS depression Details Carbidopa Butorphanol Nasal Spray Stadol® NS An increased risk of CNS depression Details Carbidopa Cetirizine Injection Aller-Tec An increased risk of CNS depression Details Carbidopa Cetirizine Ophthalmic Zerviate An increased risk of CNS depression Details Carbidopa Diazepam Nasal Spray Valtoco An increased risk of CNS depression Details Carbidopa Diazepam Rectal Diastat An increased risk of CNS depression Details Carbidopa Diphenhydramine Injection Banophen An increased risk of CNS depression Details Carbidopa Diphenhydramine Topical Afterbite with Antihistamine An increased risk of CNS depression Details Carbidopa Esketamine Nasal Spray Spravato An increased risk of CNS depression Details Carbidopa Fentanyl Transdermal Patch Duragesic® An increased risk of CNS depression Details Carbidopa Hydromorphone Injection Dilaudid An increased risk of CNS depression Details Carbidopa Hydromorphone Rectal available generically An increased risk of CNS depression Details Carbidopa Metoclopramide Injection Gimoti Diminished effectiveness of metoclopramide and the dopaminergic agent Details Carbidopa Metoclopramide Nasal Spray Gimoti Diminished effectiveness of metoclopramide and the dopaminergic agent Details Carbidopa Midazolam Nasal Spray Nayzilam An increased risk of CNS depression Details Carbidopa Midazolam Injection Nayzilam An increased risk of CNS depression Details Carbidopa Morphine Injection Astramorph® PF An increased risk of CNS depression Details Carbidopa Nalbuphine Injection Nubain® An increased risk of CNS depression Details

Moderate

Carbidopa Droxidopa Northera Decreased efficacy of droxidopa Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.