Floctafenine

91 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Floctafenine Amitriptyline Elavil Explained An increased risk of bleeding Details Floctafenine Sertraline Explained An increased risk of bleeding Details Floctafenine Apixaban Eliquis Explained An increased risk of bleeding Details Floctafenine Aspirin Acuprin® An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Floctafenine Aspirin Rectal Aspirin An increased risk of bleeding, decreased renal function, and an increased risk of gastrointestinal adverse events Details Floctafenine Betrixaban Bevyxxa® An increased risk of bleeding Details Floctafenine Anagrelide Agrylin An increased risk of bleeding Details Floctafenine Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Floctafenine Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Clopidogrel Plavix An increased risk of bleeding Details Floctafenine Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Floctafenine Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Floctafenine Dabigatran Pradaxa® An increased risk of bleeding Details Floctafenine Dabigatran Etexilate An increased risk of bleeding Details Floctafenine Dalteparin Injection Fragmin An increased risk of bleeding Details Floctafenine Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Floctafenine Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Floctafenine Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Floctafenine Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Floctafenine Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Floctafenine Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Floctafenine Dipyridamole Permole® An increased risk of bleeding Details Floctafenine Edoxaban Savaysa An increased risk of bleeding Details Floctafenine Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Floctafenine Enoxaparin Lovenox An increased risk of bleeding Details Floctafenine Enoxaparin Injection Lovenox An increased risk of bleeding Details Floctafenine Epoprostenol Flolan An increased risk of bleeding Details Floctafenine Etodolac Lodine Increased risk of bleeding Details Floctafenine Fenoprofen Fenopron Increased risk of bleeding Details Floctafenine Flurbiprofen Ansaid Increased risk of bleeding Details Floctafenine Flurbiprofen Ophthalmic Ocufen Increased risk of bleeding Details Floctafenine Fondaparinux Arixtra An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.