Sodium Zirconium Cyclosilicate

Name: Sodium Zirconium Cyclosilicate Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

2 interactions

Also sold as: Lokelma Lokelma®

About Sodium Zirconium Cyclosilicate

Sodium zirconium cyclosilicate is used to treat hyperkalemia (high levels of potassium in the blood). Sodium zirconium cyclosilicate is not used for emergency treatment of life-threatening hyperkalemia because it takes some time to work. Sodium zirconium cyclosilicate is in a class of medications called potassium remov… Read the full Sodium Zirconium Cyclosilicate drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

2 Moderate

All (2) Moderate (2)

Moderate

Sodium Zirconium Cyclosilicate Dabigatran Pradaxa® Decreased dabigatran exposure Details Sodium Zirconium Cyclosilicate Dabigatran Etexilate Decreased dabigatran exposure Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.