Triamterene
68 interactions 4 explained in plain English
Also sold as:
Dyrenium
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Dofetilide
Methotrexate Injection
Linagliptin
Hydromorphone Rectal
Perindopril
Canagliflozin
Major
Triamterene Acetaminophen And Codeine Capital® & Codeine Explained Reduced diuretic efficacy Details Triamterene Lisinopril Prinivil Explained Increased risk of hyperkalemia Details Triamterene Buprenorphine Belbuca Explained Reduced efficacy of diuretics Details Triamterene Acarbose Prandase® Explained An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Triamterene Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Triamterene Aspirin Acuprin® Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Aspirin Rectal Aspirin Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Benazepril Lotensin Increased risk of hyperkalemia Details Triamterene Alogliptin Nesina An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Bromfenac Ophthalmic Bromday® Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Canagliflozin Invokana An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Captopril Capoten® Increased risk of hyperkalemia Details Triamterene Cefepime Injection Maxipime® An increased risk of nephrotoxicity Details Triamterene Cyclosporine Injection Atopica An increased risk of hyperkalemia Details Triamterene Cyclosporine Ophthalmic Cequa An increased risk of hyperkalemia Details Triamterene Dapagliflozin Farxiga An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Diclofenac Ophthalmic Voltaren® Eye Drops Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Diclofenac Transdermal Patch Flector Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Dulaglutide Injection Trulicity An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Enalapril Epaned Increased risk of hyperkalemia Details Triamterene Etodolac Lodine Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Exenatide Injection Bydureon An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Fenoprofen Fenopron Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Fentanyl Transdermal Patch Duragesic® Reduced diuretic efficacy Details Triamterene Flurbiprofen Ansaid Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Flurbiprofen Ophthalmic Ocufen Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Folic Acid Folacin Reduced folic acid exposure Details Triamterene Fosinopril Monopril® Increased risk of hyperkalemia Details Triamterene Glimepiride Amaryl An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Glipizide Glucotrol An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Hydromorphone Injection Dilaudid Reduced efficacy of diuretics Details Triamterene Hydromorphone Rectal available generically Reduced efficacy of diuretics Details Triamterene Ibuprofen Addaprin Reduced diuretic effectiveness, hyperkalemia, or possible nephrotoxicity Details Triamterene Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hyperglycemia and an increased insulin requirement Details Triamterene Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hyperglycemia and an increased insulin requirement DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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