Amphotericin B Injection

15 interactions 357 cited references
Also sold as: Abelcet AmBisome
About Amphotericin B Injection

Amphotericin B injection is used to treat serious and potentially life-threatening fungal infections. Amphotericin B injection is in a class of medications called antifungals. It works by slowing the growth of fungi that cause infection. Read the full Amphotericin B Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Arsenic Trioxide Aspirin Bupropion Clomipramine Cyclosporine Foscarnet
10 Major 5 Moderate
All (15) Major (10) Moderate (5)

Major

Amphotericin B Injection Arsenic Trioxide Trisenox Increased risk of QT prolongation Details Amphotericin B Injection Aspirin Acuprin® Increased aspirin exposure and an increased risk of nephrotoxicity Details Amphotericin B Injection Bupropion Aplenzin Increased risk of seizures Details Amphotericin B Injection Clomipramine Anafranil Increased risk of seizures Details Amphotericin B Injection Cyclosporine Atopica An increased risk of renal dysfunction Details Amphotericin B Injection Foscarnet Foscavir Nephrotoxicity Details Amphotericin B Injection Hydroxychloroquine Plaquenil An increased risk of seizures Details Amphotericin B Injection Tacrolimus Astagraf An increased risk of nephrotoxicity Details Amphotericin B Injection Teicoplanin Increased risk of nephrotoxicity and/or ototoxicity Details Amphotericin B Injection Tramadol ConZip An increased risk of seizure Details

Moderate

Amphotericin B Injection Acetyldigoxin Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details Amphotericin B Injection Deslanoside Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details Amphotericin B Injection Digitoxin Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details Amphotericin B Injection Digoxin Cardoxin® Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details Amphotericin B Injection Metildigoxin Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.