Quinupristin

20 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Quinupristin Alfuzosin UroXatral An increase in alfuzosin exposure Details Quinupristin Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Quinupristin Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Quinupristin Diazepam Nasal Spray Valtoco An increased risk of diazepam toxicity (excessive sedation, confusion) Details Quinupristin Diazepam Rectal Diastat An increased risk of diazepam toxicity (excessive sedation, confusion) Details Quinupristin Digoxin Cardoxin® Increased digoxin levels and digoxin toxicity (nausea, vomiting, arrhythmias) Details Quinupristin Disopyramide Norpace An increased risk of disopyramide toxicity (cardiac arrhythmias, hypotension, syncope) Details Quinupristin Felodipine Plendil® An increased risk of felodipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Quinupristin Isradipine DynaCirc® An increased risk of isradipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Quinupristin Midazolam Nasal Spray Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details Quinupristin Midazolam Injection Nayzilam An increased risk of midazolam toxicity (excessive sedation, confusion) Details Quinupristin Nevirapine Viramune Increased nevirapine serum concentrations Details Quinupristin Nicardipine Cardene An increased risk of niCARdipine toxicity (dizziness, hypotension, flushing, headache, peripheral edema) Details Quinupristin Nimodipine Nimotop An increased risk of nimodipine toxicity (dizziness, headache, flushing, peripheral edema) Details Quinupristin Nisoldipine Sular An increased risk of nisoldipine toxicity (dizziness, headache, flushing, peripheral edema) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.