Rucaparib

21 interactions 2 explained in plain English
Also sold as: Rubraca Rubraca®
About Rucaparib

Rucaparib is used to help maintain the response to other treatments for certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the a… Read the full Rucaparib drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Rucaparib Relugolix Orgovyx Explained Increased relugolix exposure Details Rucaparib Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Rucaparib Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Rucaparib Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Rucaparib Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Rucaparib Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Rucaparib Digoxin Cardoxin® Increased digoxin exposure Details Rucaparib Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Rucaparib Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Rucaparib Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Rucaparib Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Rucaparib Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Rucaparib Meloxicam Injection Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Rucaparib Methylergonovine Methergine Increased methylergonovine exposure Details Rucaparib Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Rucaparib Nifedipine Adalat® Increased NIFEdipine exposure Details

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