Rucaparib

Name: Rucaparib Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

21 interactions 2 explained in plain English

Also sold as: Rubraca Rubraca®

About Rucaparib

Rucaparib is used to help maintain the response to other treatments for certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the a… Read the full Rucaparib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Morphine Injection Nifedipine Cyclosporine Injection Cyclosporine Ophthalmic Finerenone

1 Contraindicated 16 Major 4 Moderate

All (21) Contraindicated (1) Major (16) Moderate (4)

Contraindicated

Rucaparib Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.