Rucaparib

Generic name: Pronounced as (roo kap' a rib)
Brand names
  • Rubraca®
Click on drug name to hear pronunciation

Medical Content Reviewed By HelloPharmacist Staff

Last Revised - 07/15/2020

Rucaparib is used to help maintain the response to other treatments for certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), fallopian tube (tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the abdomen) cancer that has returned in adults who have completely responded or partially responded to other chemotherapy treatment(s). It is also used to treat certain types of ovarian cancer, fallopian tube cancer, and primary peritoneal cancer in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Rucaparib is also used to treat certain types of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments. Rucaparib is in a class of medications called poly (ADP-ribose) polymerase (PARP) inhibitors. It works by killing cancer cells.

Rucaparib comes as a tablet to take by mouth. It is usually taken with or without food twice daily, about 12 hours apart. Take rucaparib at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take rucaparib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor may need to delay your treatment or adjust your dose of rucaparib depending on your response to treatment and any side effects that you experience. Talk to your doctor about how you are feeling during your treatment. Do not stop taking rucaparib without talking to your doctor.

If you vomit after taking rucaparib, do not take another dose. Continue your regular dosing schedule.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Before taking rucaparib,

  • tell your doctor and pharmacist if you are allergic to rucaparib, any other medications, or any of the ingredients in rucaparib tablets. Ask your pharmacist for a list of the ingredients.

  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, you are taking or plan to take. Be sure to mention any of the following: warfarin (Coumadin, Jantoven). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with rucaparib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

  • tell your doctor if you are pregnant, plan to become pregnant, or plan to father a child. You should not become pregnant while you are taking rucaparib. You will need to take a pregnancy test before you start treatment. Use effective birth control during your treatment with rucaparib and for 6 months after your final dose. If you are a male, you and your female partner should use birth control during your treatment and for 3 months after your final dose. Talk to your doctor about birth control methods that will work for you. If you become pregnant while taking rucaparib, call your doctor.

  • tell your doctor if you plan to breastfeed. You should not breastfeed during your treatment with rucaparib and for 2 weeks after your final dose.

  • plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, a hat, sunglasses, and sunscreen. Rucaparib may make your skin sensitive to sunlight.

Unless your doctor tells you otherwise, continue your normal diet.

Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

  • Rucaparib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • nausea

    • vomiting

    • constipation

    • diarrhea

    • stomach pain

    • loss of appetite

    • bad taste in the mouth

    • itching

    • mouth sores

    • nasal congestion, runny nose, sneezing, sore or scratchy throat, or cough

  • Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • weakness, tiredness, fever, weight loss, easy bruising or bleeding, or blood in urine or stool

    • pale skin

    • shortness of breath

    • rash

  • Rucaparib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

  • If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests before you start and at various times throughout your treatment to check your body's response to rucaparib. For some conditions, your doctor will order a lab test before you begin your treatment to see whether your cancer can be treated with rucaparib.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Drug Interaction
Moxifloxacin Moxifloxacin The metabolism of Rucaparib can be decreased when combined with Moxifloxacin.
Repaglinide Repaglinide The excretion of Repaglinide can be decreased when combined with Rucaparib.
Montelukast Montelukast The metabolism of Montelukast can be decreased when combined with Rucaparib.
Insulin Glargine (rDNA origin) Injection Insulin Glargine (rDNA origin) Injection The metabolism of Rucaparib can be increased when combined with Insulin glargine.
Leflunomide Leflunomide The serum concentration of Rucaparib can be decreased when it is combined with Leflunomide.
Delavirdine Delavirdine The metabolism of Rucaparib can be decreased when combined with Delavirdine.
Nevirapine Nevirapine The metabolism of Rucaparib can be decreased when combined with Nevirapine.
Atorvastatin Atorvastatin The metabolism of Atorvastatin can be decreased when combined with Rucaparib.
Dolasetron Dolasetron The metabolism of Dolasetron can be decreased when combined with Rucaparib.
Aminophylline Aminophylline The metabolism of Aminophylline can be decreased when combined with Rucaparib.
Anagrelide Anagrelide The metabolism of Rucaparib can be increased when combined with Anagrelide.
Candesartan Candesartan The metabolism of Candesartan can be decreased when combined with Rucaparib.
Cilostazol Cilostazol The serum concentration of Cilostazol can be increased when it is combined with Rucaparib.
Clopidogrel Clopidogrel The metabolism of Clopidogrel can be decreased when combined with Rucaparib.
Erythromycin and Sulfisoxazole Erythromycin and Sulfisoxazole The serum concentration of Rucaparib can be increased when it is combined with Erythromycin.
Estrogen and Progestin (Oral Contraceptives) Estrogen and Progestin (Oral Contraceptives) The excretion of Conjugated estrogens can be decreased when combined with Rucaparib.
Fenofibrate Fenofibrate The metabolism of Fenofibrate can be decreased when combined with Rucaparib.
Guanfacine Guanfacine The risk or severity of adverse effects can be increased when Rucaparib is combined with Guanfacine.
Mycophenolate Mycophenolate The metabolism of Mycophenolic acid can be decreased when combined with Rucaparib.
Paregoric Paregoric The metabolism of Morphine can be decreased when combined with Rucaparib.
Penbutolol Penbutolol The metabolism of Acebutolol can be decreased when combined with Rucaparib.
Ranitidine Ranitidine The excretion of Ranitidine can be decreased when combined with Rucaparib.
Reserpine Reserpine The serum concentration of Rucaparib can be increased when it is combined with Reserpine.
Sumatriptan Sumatriptan Rucaparib may decrease the excretion rate of Sumatriptan which could result in a higher serum level.
Tacrolimus Tacrolimus The serum concentration of Tacrolimus can be increased when it is combined with Rucaparib.
Tizanidine Tizanidine The serum concentration of Tizanidine can be increased when it is combined with Rucaparib.
Triamcinolone Triamcinolone The metabolism of Triamcinolone can be decreased when combined with Rucaparib.
Zolmitriptan Zolmitriptan The metabolism of Zolmitriptan can be decreased when combined with Rucaparib.
Famotidine Injection Famotidine Injection The excretion of Famotidine can be decreased when combined with Rucaparib.
Fluconazole Injection Fluconazole Injection The serum concentration of Rucaparib can be increased when it is combined with Fluconazole.
Hydromorphone Injection Hydromorphone Injection The metabolism of Hydromorphone can be decreased when combined with Rucaparib.
Interferon Beta-1b Injection Interferon Beta-1b Injection The metabolism of Rucaparib can be decreased when combined with Interferon beta-1b.
Interferon Gamma-1b Injection Interferon Gamma-1b Injection The metabolism of Rucaparib can be decreased when combined with Interferon gamma-1b.
Levofloxacin Injection Levofloxacin Injection The excretion of Levofloxacin can be decreased when combined with Rucaparib.
Meperidine Injection Meperidine Injection The metabolism of Meperidine can be decreased when combined with Rucaparib.
Metoclopramide Injection Metoclopramide Injection The metabolism of Metoclopramide can be decreased when combined with Rucaparib.
Metronidazole Injection Metronidazole Injection The metabolism of Metronidazole can be decreased when combined with Rucaparib.
Morphine Injection Morphine Injection The metabolism of Morphine can be decreased when combined with Rucaparib.
Zidovudine Injection Zidovudine Injection The metabolism of Zidovudine can be decreased when combined with Rucaparib.
Altretamine Altretamine The metabolism of Amphetamine can be decreased when combined with Rucaparib.
Cyclosporine Cyclosporine The metabolism of Cyclosporine can be decreased when combined with Rucaparib.
Ondansetron Ondansetron The metabolism of Ondansetron can be decreased when combined with Rucaparib.
Torsemide Torsemide The metabolism of Torasemide can be decreased when combined with Rucaparib.
Olanzapine Olanzapine The metabolism of Rucaparib can be decreased when combined with Olanzapine.
Alosetron Alosetron The metabolism of Rucaparib can be decreased when combined with Alosetron.
Dofetilide Dofetilide The metabolism of Dofetilide can be decreased when combined with Rucaparib.
Entacapone Entacapone The metabolism of Rucaparib can be decreased when combined with Entacapone.
Hydroxychloroquine Hydroxychloroquine The metabolism of Rucaparib can be decreased when combined with Hydroxychloroquine.
Meloxicam Meloxicam The metabolism of Meloxicam can be decreased when combined with Rucaparib.
Pantoprazole Pantoprazole Pantoprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Telmisartan Telmisartan Telmisartan may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Zaleplon Zaleplon The metabolism of Zaleplon can be decreased when combined with Rucaparib.
Anakinra Anakinra The metabolism of Rucaparib can be increased when combined with Anakinra.
Trimipramine Trimipramine The metabolism of Trimipramine can be decreased when combined with Rucaparib.
Etanercept Injection Etanercept Injection The metabolism of Rucaparib can be increased when combined with Etanercept.
Modafinil Modafinil The metabolism of Rucaparib can be increased when combined with Modafinil.
Tenofovir Tenofovir The serum concentration of Tenofovir can be increased when it is combined with Rucaparib.
Sirolimus Sirolimus The serum concentration of Sirolimus can be increased when it is combined with Rucaparib.
Dutasteride Dutasteride The metabolism of Rucaparib can be decreased when combined with Dutasteride.
Epinephrine Injection Epinephrine Injection The risk or severity of adverse effects can be increased when Rucaparib is combined with Epinephrine.
Eplerenone Eplerenone The metabolism of Eplerenone can be decreased when combined with Rucaparib.
Escitalopram Escitalopram The serum concentration of Escitalopram can be increased when it is combined with Rucaparib.
Zonisamide Zonisamide The metabolism of Zonisamide can be decreased when combined with Rucaparib.
Adalimumab Injection Adalimumab Injection The metabolism of Rucaparib can be increased when combined with Adalimumab.
Aripiprazole Aripiprazole The metabolism of Aripiprazole can be decreased when combined with Rucaparib.
Atomoxetine Atomoxetine The metabolism of Atomoxetine can be decreased when combined with Rucaparib.
Ezetimibe Ezetimibe The metabolism of Ezetimibe can be decreased when combined with Rucaparib.
Atazanavir Atazanavir The metabolism of Atazanavir can be decreased when combined with Rucaparib.
Almotriptan Almotriptan The metabolism of Almotriptan can be decreased when combined with Rucaparib.
Eletriptan Eletriptan The metabolism of Eletriptan can be decreased when combined with Rucaparib.
Mefloquine Mefloquine The metabolism of Rucaparib can be decreased when combined with Mefloquine.
Rosuvastatin Rosuvastatin Rucaparib may decrease the excretion rate of Rosuvastatin which could result in a higher serum level.
Vardenafil Vardenafil The metabolism of Vardenafil can be decreased when combined with Rucaparib.
Alfuzosin Alfuzosin The metabolism of Alfuzosin can be decreased when combined with Rucaparib.
Aprepitant Aprepitant The metabolism of Aprepitant can be decreased when combined with Rucaparib.
Emtricitabine Emtricitabine The excretion of Emtricitabine can be decreased when combined with Rucaparib.
Interferon Beta-1a Subcutaneous Injection Interferon Beta-1a Subcutaneous Injection The metabolism of Rucaparib can be decreased when combined with Interferon beta-1a.
Tegaserod Tegaserod The metabolism of Rucaparib can be decreased when combined with Tegaserod.
Tadalafil Tadalafil The metabolism of Tadalafil can be decreased when combined with Rucaparib.
Frovatriptan Frovatriptan The metabolism of Rucaparib can be decreased when combined with Frovatriptan.
Gemifloxacin Gemifloxacin The metabolism of Rucaparib can be decreased when combined with Gemifloxacin.
Progesterone Progesterone The metabolism of Rucaparib can be decreased when combined with Progesterone.
Apomorphine Injection Apomorphine Injection The metabolism of Apomorphine can be decreased when combined with Rucaparib.
Darbepoetin Alfa Injection Darbepoetin Alfa Injection The risk or severity of Thrombosis can be increased when Darbepoetin alfa is combined with Rucaparib.
Infliximab Injection Infliximab Injection The metabolism of Rucaparib can be increased when combined with Infliximab.
Protriptyline Protriptyline The metabolism of Protriptyline can be decreased when combined with Rucaparib.
Rifaximin Rifaximin The serum concentration of Rifaximin can be increased when it is combined with Rucaparib.
Duloxetine Duloxetine The metabolism of Rucaparib can be decreased when combined with Duloxetine.
Norethindrone Norethindrone The metabolism of Norethisterone can be decreased when combined with Rucaparib.
Trospium Trospium The metabolism of Rucaparib can be decreased when combined with Trospium.
Bosentan Bosentan The metabolism of Bosentan can be decreased when combined with Rucaparib.
Cefditoren Cefditoren The excretion of Cefdinir can be decreased when combined with Rucaparib.
Cinacalcet Cinacalcet The metabolism of Rucaparib can be decreased when combined with Cinacalcet.
Erlotinib Erlotinib The metabolism of Rucaparib can be decreased when combined with Erlotinib.
Eszopiclone Eszopiclone The metabolism of Eszopiclone can be decreased when combined with Rucaparib.
Ganciclovir Ganciclovir The excretion of Ganciclovir can be decreased when combined with Rucaparib.
Solifenacin Solifenacin The metabolism of Solifenacin can be decreased when combined with Rucaparib.
Voriconazole Voriconazole The metabolism of Voriconazole can be decreased when combined with Rucaparib.
Dextroamphetamine Dextroamphetamine The metabolism of Amphetamine can be decreased when combined with Rucaparib.
Entecavir Entecavir The metabolism of Rucaparib can be decreased when combined with Entecavir.
Peginterferon Alfa-2a Injection Peginterferon Alfa-2a Injection The metabolism of Rucaparib can be decreased when combined with Peginterferon alfa-2a.
Peginterferon Alfa-2b (PEG-Intron) Peginterferon Alfa-2b (PEG-Intron) The serum concentration of Rucaparib can be increased when it is combined with Peginterferon alfa-2b.
Ramelteon Ramelteon The metabolism of Ramelteon can be decreased when combined with Rucaparib.
Darifenacin Darifenacin The metabolism of Darifenacin can be decreased when combined with Rucaparib.
Fentanyl Fentanyl The metabolism of Fentanyl can be decreased when combined with Rucaparib.
Deferasirox Deferasirox The serum concentration of Rucaparib can be increased when it is combined with Deferasirox.
Phenylephrine Phenylephrine The metabolism of Rucaparib can be increased when combined with Phenylephrine.
Tipranavir Tipranavir The metabolism of Tipranavir can be decreased when combined with Rucaparib.
Ranolazine Ranolazine The serum concentration of Rucaparib can be increased when it is combined with Ranolazine.
Abatacept Injection Abatacept Injection The metabolism of Rucaparib can be increased when combined with Abatacept.
Rasagiline Rasagiline The metabolism of Rucaparib can be decreased when combined with Rasagiline.
Imatinib Imatinib The metabolism of Rucaparib can be decreased when combined with Imatinib.
Sitagliptin Sitagliptin The serum concentration of Sitagliptin can be increased when it is combined with Rucaparib.
Gefitinib Gefitinib The metabolism of Rucaparib can be decreased when combined with Gefitinib.
Paliperidone Paliperidone The metabolism of Rucaparib can be decreased when combined with Paliperidone.
Bortezomib Bortezomib The metabolism of Rucaparib can be decreased when combined with Bortezomib.
Clofarabine Injection Clofarabine Injection The excretion of Clofarabine can be decreased when combined with Rucaparib.
Fulvestrant Injection Fulvestrant Injection The metabolism of Fulvestrant can be decreased when combined with Rucaparib.
Insulin Glulisine (rDNA origin) Injection Insulin Glulisine (rDNA origin) Injection The metabolism of Rucaparib can be increased when combined with Insulin glulisine.
Oxaliplatin Injection Oxaliplatin Injection Rucaparib may decrease the excretion rate of Oxaliplatin which could result in a higher serum level.
Posaconazole Posaconazole The serum concentration of Rucaparib can be increased when it is combined with Posaconazole.
Primaquine Primaquine The metabolism of Rucaparib can be decreased when combined with Primaquine.
Pemetrexed Injection Pemetrexed Injection The excretion of Rucaparib can be decreased when combined with Pemetrexed.
Lisdexamfetamine Lisdexamfetamine The metabolism of Lisdexamfetamine can be decreased when combined with Rucaparib.
Retapamulin Retapamulin The metabolism of Retapamulin can be decreased when combined with Rucaparib.
Sorafenib Sorafenib The metabolism of Rucaparib can be decreased when combined with Sorafenib.
Sunitinib Sunitinib The metabolism of Rucaparib can be decreased when combined with Sunitinib.
Dronabinol Dronabinol Dronabinol may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Lapatinib Lapatinib The serum concentration of Rucaparib can be increased when it is combined with Lapatinib.
Dasatinib Dasatinib The metabolism of Dasatinib can be decreased when combined with Rucaparib.
Mexiletine Mexiletine The metabolism of Rucaparib can be decreased when combined with Mexiletine.
Armodafinil Armodafinil The metabolism of Rucaparib can be increased when combined with Armodafinil.
Ivermectin Ivermectin Rucaparib may decrease the excretion rate of Ivermectin which could result in a higher serum level.
Temsirolimus Temsirolimus The serum concentration of Temsirolimus can be increased when it is combined with Rucaparib.
Nilotinib Nilotinib The metabolism of Rucaparib can be decreased when combined with Nilotinib.
Toremifene Toremifene The serum concentration of Rucaparib can be increased when it is combined with Toremifene.
Raltegravir Raltegravir The metabolism of Raltegravir can be decreased when combined with Rucaparib.
Bexarotene Bexarotene The metabolism of Bexarotene can be decreased when combined with Rucaparib.
Doripenem Injection Doripenem Injection The excretion of Doripenem can be decreased when combined with Rucaparib.
Etravirine Etravirine The metabolism of Etravirine can be decreased when combined with Rucaparib.
Mitoxantrone Injection Mitoxantrone Injection Rucaparib may decrease the excretion rate of Mitoxantrone which could result in a higher serum level.
Desvenlafaxine Desvenlafaxine The metabolism of Rucaparib can be decreased when combined with Desvenlafaxine.
Cevimeline Cevimeline The metabolism of Cevimeline can be decreased when combined with Rucaparib.
Nebivolol Nebivolol The metabolism of Nebivolol can be decreased when combined with Rucaparib.
Tretinoin Tretinoin The metabolism of Tretinoin can be decreased when combined with Rucaparib.
Bendamustine Injection Bendamustine Injection The serum concentration of Rucaparib can be increased when it is combined with Bendamustine.
Leucovorin Injection Leucovorin Injection The excretion of Leucovorin can be decreased when combined with Rucaparib.
Flecainide Flecainide The metabolism of Flecainide can be decreased when combined with Rucaparib.
Certolizumab Injection Certolizumab Injection The metabolism of Rucaparib can be increased when combined with Certolizumab pegol.
Ixabepilone Injection Ixabepilone Injection The metabolism of Ixabepilone can be decreased when combined with Rucaparib.
Irinotecan Injection Irinotecan Injection The risk or severity of neutropenia can be increased when Rucaparib is combined with Irinotecan.
Praziquantel Praziquantel The metabolism of Rucaparib can be decreased when combined with Praziquantel.
Rufinamide Rufinamide The metabolism of Rufinamide can be decreased when combined with Rucaparib.
Silodosin Silodosin The serum concentration of Silodosin can be increased when it is combined with Rucaparib.
Midazolam Midazolam The serum concentration of Midazolam can be increased when it is combined with Rucaparib.
Naltrexone Injection Naltrexone Injection The metabolism of Naltrexone can be decreased when combined with Rucaparib.
Eltrombopag Eltrombopag The metabolism of Eltrombopag can be decreased when combined with Rucaparib.
Dexlansoprazole Dexlansoprazole The metabolism of Dexlansoprazole can be decreased when combined with Rucaparib.
Fesoterodine Fesoterodine The metabolism of Fesoterodine can be decreased when combined with Rucaparib.
Betaxolol Betaxolol The metabolism of Rucaparib can be decreased when combined with Betaxolol.
Iloperidone Iloperidone The metabolism of Iloperidone can be decreased when combined with Rucaparib.
Prasugrel Prasugrel The metabolism of Prasugrel can be decreased when combined with Rucaparib.
Lacosamide Lacosamide The metabolism of Lacosamide can be decreased when combined with Rucaparib.
Everolimus Everolimus The serum concentration of Everolimus can be increased when it is combined with Rucaparib.
Tolvaptan (low blood sodium) Tolvaptan (low blood sodium) The serum concentration of Tolvaptan can be increased when it is combined with Rucaparib.
Dronedarone Dronedarone The metabolism of Dronedarone can be decreased when combined with Rucaparib.
Pralatrexate Injection Pralatrexate Injection Rucaparib may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
Palonosetron Injection Palonosetron Injection The metabolism of Palonosetron can be decreased when combined with Rucaparib.
Saxagliptin Saxagliptin The excretion of Saxagliptin can be decreased when combined with Rucaparib.
Romidepsin Injection Romidepsin Injection The serum concentration of Romidepsin can be increased when it is combined with Rucaparib.
Tapentadol Tapentadol The metabolism of Tapentadol can be decreased when combined with Rucaparib.
Topotecan Topotecan The serum concentration of Topotecan can be increased when it is combined with Rucaparib.
Golimumab Injection Golimumab Injection The metabolism of Rucaparib can be increased when combined with Golimumab.
Pazopanib Pazopanib The serum concentration of Pazopanib can be increased when it is combined with Rucaparib.
Asenapine Asenapine The metabolism of Rucaparib can be decreased when combined with Asenapine.
Pitavastatin Pitavastatin Rucaparib may decrease the excretion rate of Pitavastatin which could result in a higher serum level.
Albendazole Albendazole The metabolism of Albendazole can be increased when combined with Rucaparib.
Levonorgestrel Levonorgestrel The metabolism of Rucaparib can be decreased when combined with Levonorgestrel.
Oxymorphone Oxymorphone The metabolism of Oxymorphone can be decreased when combined with Rucaparib.
Tocilizumab Injection Tocilizumab Injection The metabolism of Rucaparib can be increased when combined with Tocilizumab.
Cabazitaxel Injection Cabazitaxel Injection The serum concentration of Rucaparib can be increased when it is combined with Cabazitaxel.
Acetaminophen Injection Acetaminophen Injection The metabolism of Acetaminophen can be decreased when combined with Rucaparib.
Vilazodone Vilazodone The metabolism of Rucaparib can be decreased when combined with Vilazodone.
Busulfan Injection Busulfan Injection The metabolism of Busulfan can be decreased when combined with Rucaparib.
Roflumilast Roflumilast The metabolism of Rucaparib can be decreased when combined with Roflumilast.
Linagliptin Linagliptin The serum concentration of Rucaparib can be increased when it is combined with Linagliptin.
Rilpivirine Rilpivirine Rilpivirine may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Telaprevir Telaprevir The serum concentration of Glecaprevir can be increased when it is combined with Rucaparib.
Cyclophosphamide Injection Cyclophosphamide Injection The metabolism of Cyclophosphamide can be decreased when combined with Rucaparib.
Abiraterone Abiraterone The serum concentration of Rucaparib can be increased when it is combined with Abiraterone.
Rivaroxaban Rivaroxaban Rucaparib may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
Ticagrelor Ticagrelor The serum concentration of Rucaparib can be increased when it is combined with Ticagrelor.
Brentuximab Vedotin Injection Brentuximab Vedotin Injection The serum concentration of Brentuximab vedotin can be increased when it is combined with Rucaparib.
Ruxolitinib Ruxolitinib The metabolism of Ruxolitinib can be decreased when combined with Rucaparib.
Vandetanib Vandetanib The metabolism of Rucaparib can be decreased when combined with Vandetanib.
Clobazam Clobazam The metabolism of Clobazam can be decreased when combined with Rucaparib.
Vemurafenib Vemurafenib The serum concentration of Rucaparib can be increased when it is combined with Vemurafenib.
Vismodegib Vismodegib Vismodegib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Ivacaftor Ivacaftor The serum concentration of Rucaparib can be increased when it is combined with Ivacaftor.
Axitinib Axitinib The metabolism of Axitinib can be decreased when combined with Rucaparib.
Crizotinib Crizotinib The serum concentration of Rucaparib can be increased when it is combined with Crizotinib.
Cabergoline Cabergoline The metabolism of Cabergoline can be decreased when combined with Rucaparib.
Naloxone Injection Naloxone Injection The metabolism of Naloxone can be decreased when combined with Rucaparib.
Ambrisentan Ambrisentan The serum concentration of Ambrisentan can be increased when it is combined with Rucaparib.
Ezogabine Ezogabine The metabolism of Tiagabine can be decreased when combined with Rucaparib.
Carfilzomib Injection Carfilzomib Injection The serum concentration of Carfilzomib can be increased when it is combined with Rucaparib.
Enzalutamide Enzalutamide The serum concentration of Rucaparib can be increased when it is combined with Enzalutamide.
Mirabegron Mirabegron The metabolism of Rucaparib can be decreased when combined with Mirabegron.
Regorafenib Regorafenib The serum concentration of Rucaparib can be increased when it is combined with Regorafenib.
Bosutinib Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Rucaparib.
Teriflunomide Teriflunomide The serum concentration of Rucaparib can be decreased when it is combined with Teriflunomide.
Cabozantinib (thyroid cancer) Cabozantinib (thyroid cancer) The metabolism of Cabozantinib can be decreased when combined with Rucaparib.
Tofacitinib Tofacitinib The metabolism of Tofacitinib can be decreased when combined with Rucaparib.
Alogliptin Alogliptin The metabolism of Alogliptin can be decreased when combined with Rucaparib.
Ponatinib Ponatinib The metabolism of Rucaparib can be decreased when combined with Ponatinib.
Pomalidomide Pomalidomide The serum concentration of Pomalidomide can be increased when it is combined with Rucaparib.
Ado-trastuzumab Emtansine Injection Ado-trastuzumab Emtansine Injection The serum concentration of Trastuzumab emtansine can be increased when it is combined with Rucaparib.
Apixaban Apixaban The serum concentration of Apixaban can be increased when it is combined with Rucaparib.
Canagliflozin Canagliflozin The serum concentration of Rucaparib can be increased when it is combined with Canagliflozin.
Dabrafenib Dabrafenib The serum concentration of Rucaparib can be increased when it is combined with Dabrafenib.
Ospemifene Ospemifene The metabolism of Ospemifene can be decreased when combined with Rucaparib.
Dolutegravir Dolutegravir The metabolism of Dolutegravir can be decreased when combined with Rucaparib.
Afatinib Afatinib The serum concentration of Afatinib can be increased when it is combined with Rucaparib.
Levomilnacipran Levomilnacipran The metabolism of Levomilnacipran can be decreased when combined with Rucaparib.
Vortioxetine Vortioxetine The metabolism of Vortioxetine can be decreased when combined with Rucaparib.
Perampanel Perampanel The metabolism of Rucaparib can be decreased when combined with Perampanel.
Ibrutinib Ibrutinib The metabolism of Ibrutinib can be decreased when combined with Rucaparib.
Lomitapide Lomitapide The metabolism of Lomitapide can be decreased when combined with Rucaparib.
Ketorolac Injection Ketorolac Injection The metabolism of Ketorolac can be decreased when combined with Rucaparib.
Simeprevir Simeprevir The metabolism of Rucaparib can be decreased when combined with Simeprevir.
Sofosbuvir Sofosbuvir The serum concentration of Sofosbuvir can be increased when it is combined with Rucaparib.
Dapagliflozin Dapagliflozin The metabolism of Dapagliflozin can be decreased when combined with Rucaparib.
Apremilast Apremilast The metabolism of Rucaparib can be increased when combined with Apremilast.
Ceritinib Ceritinib The serum concentration of Ceritinib can be increased when it is combined with Rucaparib.
Siltuximab Injection Siltuximab Injection The metabolism of Rucaparib can be increased when combined with Siltuximab.
Eslicarbazepine Eslicarbazepine The metabolism of Eslicarbazepine can be decreased when combined with Rucaparib.
Belinostat Injection Belinostat Injection The metabolism of Belinostat can be decreased when combined with Rucaparib.
Idelalisib Idelalisib The metabolism of Rucaparib can be decreased when combined with Idelalisib.
Testosterone Injection Testosterone Injection Rucaparib may decrease the excretion rate of Testosterone which could result in a higher serum level.
Oritavancin Injection Oritavancin Injection The metabolism of Rucaparib can be decreased when combined with Oritavancin.
Vorapaxar Vorapaxar The serum concentration of Rucaparib can be increased when it is combined with Vorapaxar.
Hydrocodone Hydrocodone The metabolism of Hydrocodone can be decreased when combined with Rucaparib.
Suvorexant Suvorexant The serum concentration of Rucaparib can be increased when it is combined with Suvorexant.
Edoxaban Edoxaban The serum concentration of Edoxaban can be increased when it is combined with Rucaparib.
Peginterferon Beta-1a Injection Peginterferon Beta-1a Injection The metabolism of Rucaparib can be decreased when combined with Peginterferon beta-1a.
Olaparib Olaparib The metabolism of Rucaparib can be decreased when combined with Olaparib.
Caspofungin Injection Caspofungin Injection The excretion of Caspofungin can be decreased when combined with Rucaparib.
Methamphetamine Methamphetamine The metabolism of Metamfetamine can be decreased when combined with Rucaparib.
Tasimelteon Tasimelteon The metabolism of Rucaparib can be decreased when combined with Tasimelteon.
Riociguat Riociguat Rucaparib may decrease the excretion rate of Riociguat which could result in a higher serum level.
Pirfenidone Pirfenidone The metabolism of Pirfenidone can be increased when combined with Rucaparib.
Nintedanib Nintedanib The serum concentration of Nintedanib can be increased when it is combined with Rucaparib.
Secukinumab Injection Secukinumab Injection The metabolism of Rucaparib can be increased when combined with Secukinumab.
Risperidone Injection Risperidone Injection The metabolism of Rucaparib can be decreased when combined with Risperidone.
Palbociclib Palbociclib The metabolism of Rucaparib can be decreased when combined with Palbociclib.
Insulin Human Inhalation Insulin Human Inhalation The metabolism of Rucaparib can be increased when combined with Insulin human.
Lenvatinib Lenvatinib The serum concentration of Lenvatinib can be increased when it is combined with Rucaparib.
Naloxegol Naloxegol The serum concentration of Naloxegol can be increased when it is combined with Rucaparib.
Panobinostat Panobinostat The metabolism of Panobinostat can be decreased when combined with Rucaparib.
Haloperidol Injection Haloperidol Injection The serum concentration of Rucaparib can be increased when it is combined with Haloperidol.
Isavuconazonium Injection Isavuconazonium Injection The serum concentration of Rucaparib can be increased when it is combined with Isavuconazonium.
Sonidegib Sonidegib The metabolism of Sonidegib can be decreased when combined with Rucaparib.
Flibanserin Flibanserin The serum concentration of Rucaparib can be increased when it is combined with Flibanserin.
Rolapitant Rolapitant The metabolism of Rucaparib can be decreased when combined with Rolapitant.
Daclatasvir Daclatasvir The serum concentration of Rucaparib can be increased when it is combined with Daclatasvir.
Brexpiprazole Brexpiprazole The metabolism of Brexpiprazole can be decreased when combined with Rucaparib.
Ziprasidone Injection Ziprasidone Injection The metabolism of Ziprasidone can be decreased when combined with Rucaparib.
Cariprazine Cariprazine The metabolism of Cariprazine can be decreased when combined with Rucaparib.
Eluxadoline Eluxadoline The serum concentration of Eluxadoline can be increased when it is combined with Rucaparib.
Insulin Degludec (rDNA Origin) Injection Insulin Degludec (rDNA Origin) Injection The metabolism of Rucaparib can be increased when combined with Insulin degludec.
Cobimetinib Cobimetinib The serum concentration of Cobimetinib can be increased when it is combined with Rucaparib.
Trabectedin Injection Trabectedin Injection The metabolism of Trabectedin can be decreased when combined with Rucaparib.
Osimertinib Osimertinib The serum concentration of Rucaparib can be decreased when it is combined with Osimertinib.
Alectinib Alectinib The metabolism of Rucaparib can be decreased when combined with Alectinib.
Ixazomib Ixazomib The metabolism of Ixazomib can be decreased when combined with Rucaparib.
Lesinurad Lesinurad The metabolism of Lesinurad can be decreased when combined with Rucaparib.
Dexamethasone Injection Dexamethasone Injection The excretion of Dexamethasone can be decreased when combined with Rucaparib.
Brivaracetam Injection Brivaracetam Injection The metabolism of Brivaracetam can be decreased when combined with Rucaparib.
Venetoclax Venetoclax The metabolism of Rucaparib can be decreased when combined with Venetoclax.
Cobicistat Cobicistat The serum concentration of Rucaparib can be increased when it is combined with Cobicistat.
Selexipag Selexipag The serum concentration of Selexipag can be increased when it is combined with Rucaparib.
Obeticholic Acid Obeticholic Acid The metabolism of Rucaparib can be decreased when combined with Obeticholic acid.
Diphenhydramine Injection Diphenhydramine Injection The metabolism of Diphenhydramine can be decreased when combined with Rucaparib.
Furosemide Injection Furosemide Injection The metabolism of Furosemide can be decreased when combined with Rucaparib.
Ribociclib Ribociclib The metabolism of Ribociclib can be decreased when combined with Rucaparib.
Brigatinib Brigatinib The metabolism of Rucaparib can be decreased when combined with Brigatinib.
Doxepin (Insomnia) Doxepin (Insomnia) The metabolism of Doxepin can be decreased when combined with Rucaparib.
Deutetrabenazine Deutetrabenazine The metabolism of Deutetrabenazine can be decreased when combined with Rucaparib.
Valbenazine Valbenazine The metabolism of Valbenazine can be decreased when combined with Rucaparib.
Safinamide Safinamide Safinamide may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Edaravone Injection Edaravone Injection The excretion of Edaravone can be decreased when combined with Rucaparib.
Midostaurin Midostaurin The metabolism of Rucaparib can be decreased when combined with Midostaurin.
Neratinib Neratinib The metabolism of Rucaparib can be decreased when combined with Neratinib.
Enasidenib Enasidenib The metabolism of Enasidenib can be decreased when combined with Rucaparib.
Inotuzumab Ozogamicin Injection Inotuzumab Ozogamicin Injection The serum concentration of Inotuzumab ozogamicin can be increased when it is combined with Rucaparib.
Aprepitant/Fosaprepitant Injection Aprepitant/Fosaprepitant Injection The metabolism of Fosaprepitant can be decreased when combined with Rucaparib.
Copanlisib Injection Copanlisib Injection The serum concentration of Copanlisib can be increased when it is combined with Rucaparib.
Delafloxacin Delafloxacin The metabolism of Delafloxacin can be decreased when combined with Rucaparib.
Abemaciclib Abemaciclib The metabolism of Abemaciclib can be decreased when combined with Rucaparib.
Betrixaban Betrixaban The serum concentration of Betrixaban can be increased when it is combined with Rucaparib.
Acalabrutinib Acalabrutinib The metabolism of Acalabrutinib can be decreased when combined with Rucaparib.
Letermovir Letermovir The metabolism of Letermovir can be decreased when combined with Rucaparib.
Tetrabenazine Tetrabenazine The metabolism of Tetrabenazine can be decreased when combined with Rucaparib.
Ertugliflozin Ertugliflozin The serum concentration of Ertugliflozin can be increased when it is combined with Rucaparib.
Buprenorphine Injection Buprenorphine Injection The metabolism of Buprenorphine can be decreased when combined with Rucaparib.
Apalutamide Apalutamide The serum concentration of Rucaparib can be decreased when it is combined with Apalutamide.
Penicillamine Penicillamine The excretion of Penicillamine can be decreased when combined with Rucaparib.
Fostamatinib Fostamatinib Fostamatinib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Avatrombopag Avatrombopag The serum concentration of Avatrombopag can be increased when it is combined with Rucaparib.
Baricitinib Baricitinib The metabolism of Baricitinib can be decreased when combined with Rucaparib.
Lofexidine Lofexidine The metabolism of Rucaparib can be decreased when combined with Lofexidine.
Eliglustat Eliglustat The metabolism of Eliglustat can be decreased when combined with Rucaparib.
Encorafenib Encorafenib The metabolism of Encorafenib can be decreased when combined with Rucaparib.
Binimetinib Binimetinib The serum concentration of Binimetinib can be increased when it is combined with Rucaparib.
Ivosidenib Ivosidenib The metabolism of Ivosidenib can be decreased when combined with Rucaparib.
Lusutrombopag Lusutrombopag The serum concentration of Lusutrombopag can be increased when it is combined with Rucaparib.
Elagolix Elagolix The metabolism of Elagolix can be decreased when combined with Rucaparib.
Doravirine Doravirine The metabolism of Rucaparib can be decreased when combined with Doravirine.
Tafenoquine Tafenoquine The metabolism of Tafenoquine can be decreased when combined with Rucaparib.
Cannabidiol Cannabidiol Cannabidiol may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Dacomitinib Dacomitinib The metabolism of Rucaparib can be decreased when combined with Dacomitinib.
Duvelisib Duvelisib The serum concentration of Duvelisib can be increased when it is combined with Rucaparib.
Omadacycline Omadacycline The serum concentration of Omadacycline can be increased when it is combined with Rucaparib.
Sarecycline Sarecycline The serum concentration of Rucaparib can be increased when it is combined with Sarecycline.
Stiripentol Stiripentol The metabolism of Rucaparib can be decreased when combined with Stiripentol.
Talazoparib Talazoparib The serum concentration of Talazoparib can be increased when it is combined with Rucaparib.
Gilteritinib Gilteritinib Gilteritinib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Glasdegib Glasdegib Glasdegib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Lorlatinib Lorlatinib The metabolism of Lorlatinib can be decreased when combined with Rucaparib.
Larotrectinib Larotrectinib The serum concentration of Larotrectinib can be increased when it is combined with Rucaparib.
Methoxy Polyethylene Glycol-Epoetin Beta Injection Methoxy Polyethylene Glycol-Epoetin Beta Injection The risk or severity of Thrombosis can be increased when Methoxy polyethylene glycol-epoetin beta is combined with Rucaparib.
Paclitaxel (with albumin) Injection Paclitaxel (with albumin) Injection The metabolism of Paclitaxel can be decreased when combined with Rucaparib.
Rifamycin Rifamycin The serum concentration of Rucaparib can be increased when it is combined with Rifamycin.
Prucalopride Prucalopride The serum concentration of Prucalopride can be increased when it is combined with Rucaparib.
Emapalumab-lzsg Injection Emapalumab-lzsg Injection The metabolism of Rucaparib can be increased when combined with Emapalumab.
Siponimod Siponimod The metabolism of Siponimod can be decreased when combined with Rucaparib.
Acyclovir Ophthalmic Acyclovir Ophthalmic The metabolism of Rucaparib can be decreased when combined with Acyclovir.
Erdafitinib Erdafitinib The serum concentration of Rucaparib can be increased when it is combined with Erdafitinib.
Esomeprazole Injection Esomeprazole Injection The metabolism of Esomeprazole can be decreased when combined with Rucaparib.
Alpelisib Alpelisib The serum concentration of Alpelisib can be increased when it is combined with Rucaparib.
Cladribine Cladribine Rucaparib may decrease the excretion rate of Cladribine which could result in a higher serum level.
Solriamfetol Solriamfetol The excretion of Solriamfetol can be decreased when combined with Rucaparib.
Darolutamide Darolutamide The serum concentration of Darolutamide can be increased when it is combined with Rucaparib.
Triclabendazole Triclabendazole The metabolism of Rucaparib can be decreased when combined with Triclabendazole.
Entrectinib Entrectinib The metabolism of Entrectinib can be decreased when combined with Rucaparib.
Pexidartinib Pexidartinib The metabolism of Pexidartinib can be decreased when combined with Rucaparib.
Istradefylline Istradefylline The metabolism of Istradefylline can be decreased when combined with Rucaparib.
Pitolisant Pitolisant The serum concentration of Rucaparib can be decreased when it is combined with Pitolisant.
Fedratinib Fedratinib Fedratinib may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Lefamulin Lefamulin Rucaparib may decrease the excretion rate of Lefamulin which could result in a higher serum level.
Phenytoin Injection Phenytoin Injection The metabolism of Phenytoin can be decreased when combined with Rucaparib.
Fosphenytoin Injection Fosphenytoin Injection The metabolism of Fosphenytoin can be decreased when combined with Rucaparib.
Enfortumab vedotin-ejfv Injection Enfortumab vedotin-ejfv Injection The serum concentration of Enfortumab vedotin can be increased when it is combined with Rucaparib.
Zanubrutinib Zanubrutinib The metabolism of Zanubrutinib can be decreased when combined with Rucaparib.
Voxelotor Voxelotor The serum concentration of Voxelotor can be increased when it is combined with Rucaparib.
Avapritinib Avapritinib The metabolism of Avapritinib can be decreased when combined with Rucaparib.
Lumateperone Lumateperone The serum concentration of Lumateperone can be increased when it is combined with Rucaparib.
Lasmiditan Lasmiditan The serum concentration of Rucaparib can be increased when it is combined with Lasmiditan.
Ubrogepant Ubrogepant The serum concentration of Ubrogepant can be increased when it is combined with Rucaparib.
Tazemetostat Tazemetostat Rucaparib may decrease the excretion rate of Tazemetostat which could result in a higher serum level.
Bempedoic Acid Bempedoic Acid The excretion of Bempedoic acid can be decreased when combined with Rucaparib.
Cenobamate Cenobamate The serum concentration of Cenobamate can be decreased when it is combined with Rucaparib.
Ozanimod Ozanimod Rucaparib may decrease the excretion rate of Ozanimod which could result in a higher serum level.
Selumetinib Selumetinib Rucaparib may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Rimegepant Rimegepant The serum concentration of Rimegepant can be increased when it is combined with Rucaparib.
Tucatinib Tucatinib Rucaparib may decrease the excretion rate of Tucatinib which could result in a higher serum level.
Remdesivir Injection Remdesivir Injection The serum concentration of Remdesivir can be increased when it is combined with Rucaparib.
Sacituzumab govitecan-hziy Injection Sacituzumab govitecan-hziy Injection The serum concentration of Sacituzumab govitecan can be increased when it is combined with Rucaparib.
Ripretinib Ripretinib Rucaparib may decrease the excretion rate of Ripretinib which could result in a higher serum level.
Capmatinib Capmatinib The serum concentration of Rucaparib can be increased when it is combined with Capmatinib.
Lemborexant Lemborexant The metabolism of Lemborexant can be decreased when combined with Rucaparib.
Fenfluramine Fenfluramine The metabolism of Rucaparib can be decreased when combined with Fenfluramine.
Fostemsavir Fostemsavir Fostemsavir may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Belantamab Mafodotin-blmf Injection Belantamab Mafodotin-blmf Injection The serum concentration of Belantamab mafodotin can be increased when it is combined with Rucaparib.
Pralsetinib Pralsetinib The serum concentration of Pralsetinib can be increased when it is combined with Rucaparib.
Satralizumab-mwge Injection Satralizumab-mwge Injection The serum concentration of Rucaparib can be decreased when it is combined with Satralizumab.
Relugolix Relugolix The serum concentration of Relugolix can be increased when it is combined with Rucaparib.
Progestin-Only (drospirenone) Oral Contraceptives Progestin-Only (drospirenone) Oral Contraceptives The metabolism of Drospirenone can be decreased when combined with Rucaparib.
Viloxazine Viloxazine The metabolism of Rucaparib can be decreased when combined with Viloxazine.
Theophylline Theophylline The metabolism of Theophylline can be decreased when combined with Rucaparib.
Indomethacin Indomethacin The metabolism of Indomethacin can be decreased when combined with Rucaparib.
Mefenamic Acid Mefenamic Acid The metabolism of Mefenamic acid can be decreased when combined with Rucaparib.
Naproxen Naproxen The metabolism of Naproxen can be decreased when combined with Rucaparib.
Trazodone Trazodone The metabolism of Trazodone can be decreased when combined with Rucaparib.
Hydroxyurea Hydroxyurea The metabolism of Rucaparib can be decreased when combined with Hydroxyurea.
Phenobarbital Phenobarbital The metabolism of Phenobarbital can be decreased when combined with Rucaparib.
Methotrexate Injection Methotrexate Injection The metabolism of Methotrexate can be decreased when combined with Rucaparib.
Primidone Primidone The metabolism of Primidone can be increased when combined with Rucaparib.
Methsuximide Methsuximide The metabolism of Methsuximide can be decreased when combined with Rucaparib.
Chlorpromazine Chlorpromazine The metabolism of Rucaparib can be decreased when combined with Chlorpromazine.
Diazepam Diazepam The metabolism of Diazepam can be decreased when combined with Rucaparib.
Lorazepam Lorazepam The metabolism of Rucaparib can be decreased when combined with Lorazepam.
Carmustine Carmustine The metabolism of Rucaparib can be decreased when combined with Carmustine.
Amantadine Amantadine The risk or severity of adverse effects can be increased when Rucaparib is combined with Amantadine.
Codeine Codeine The metabolism of Codeine can be decreased when combined with Rucaparib.
Tranylcypromine Tranylcypromine The metabolism of Rucaparib can be decreased when combined with Tranylcypromine.
Phenelzine Phenelzine The metabolism of Rucaparib can be decreased when combined with Phenelzine.
Tetracycline Tetracycline The excretion of Tetracycline can be decreased when combined with Rucaparib.
Prochlorperazine Prochlorperazine The metabolism of Prochlorperazine can be decreased when combined with Rucaparib.
Thioridazine Thioridazine The metabolism of Rucaparib can be decreased when combined with Thioridazine.
Trifluoperazine Trifluoperazine The metabolism of Trifluoperazine can be increased when combined with Rucaparib.
Dapsone Dapsone The metabolism of Dapsone can be decreased when combined with Rucaparib.
Sulfadiazine Sulfadiazine The metabolism of Sulfadiazine can be decreased when combined with Rucaparib.
Oxycodone Oxycodone The metabolism of Oxycodone can be decreased when combined with Rucaparib.
Methadone Methadone The metabolism of Rucaparib can be decreased when combined with Methadone.
Oxybutynin Oxybutynin The metabolism of Oxybutynin can be decreased when combined with Rucaparib.
Benztropine Benztropine The metabolism of Benzatropine can be decreased when combined with Rucaparib.
Maprotiline Maprotiline The metabolism of Rucaparib can be decreased when combined with Maprotiline.
Ibuprofen Ibuprofen The metabolism of Ibuprofen can be decreased when combined with Rucaparib.
Orphenadrine Orphenadrine The metabolism of Rucaparib can be decreased when combined with Orphenadrine.
Perphenazine Perphenazine The metabolism of Rucaparib can be decreased when combined with Perphenazine.
Azathioprine Azathioprine The metabolism of Rucaparib can be decreased when combined with Azathioprine.
Fluphenazine Fluphenazine The metabolism of Rucaparib can be decreased when combined with Fluphenazine.
Phentermine Phentermine The metabolism of Rucaparib can be decreased when combined with Phentermine.
Amoxapine Amoxapine The metabolism of Amoxapine can be decreased when combined with Rucaparib.
Sulfasalazine Sulfasalazine Sulfasalazine may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Hydrocortisone Hydrocortisone The excretion of Hydrocortisone can be decreased when combined with Rucaparib.
Doxorubicin Doxorubicin The serum concentration of Doxorubicin can be increased when it is combined with Rucaparib.
Cytarabine Cytarabine The risk or severity of adverse effects can be increased when Rucaparib is combined with Cytarabine.
Dactinomycin Dactinomycin The serum concentration of Rucaparib can be increased when it is combined with Dactinomycin.
Carbamazepine Carbamazepine The metabolism of Carbamazepine can be decreased when combined with Rucaparib.
Clonidine Clonidine The metabolism of Clonidine can be decreased when combined with Rucaparib.
Prazosin Prazosin Rucaparib may decrease the excretion rate of Prazosin which could result in a higher serum level.
Cimetidine Cimetidine The metabolism of Cimetidine can be decreased when combined with Rucaparib.
Warfarin Warfarin The serum concentration of Warfarin can be increased when it is combined with Rucaparib.
Loperamide Loperamide The metabolism of Rucaparib can be decreased when combined with Loperamide.
Promethazine Promethazine The metabolism of Rucaparib can be decreased when combined with Promethazine.
Daunorubicin Daunorubicin Rucaparib may decrease the excretion rate of Daunorubicin which could result in a higher serum level.
Nitrofurantoin Nitrofurantoin Rucaparib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Griseofulvin Griseofulvin The metabolism of Rucaparib can be increased when combined with Griseofulvin.
Digoxin Digoxin Rucaparib may decrease the excretion rate of Digoxin which could result in a higher serum level.
Loxapine Loxapine The serum concentration of Rucaparib can be increased when it is combined with Loxapine.
Chloroquine Chloroquine The metabolism of Rucaparib can be decreased when combined with Chloroquine.
Quinine Quinine The metabolism of Rucaparib can be decreased when combined with Quinine.
Triamterene Triamterene The metabolism of Rucaparib can be decreased when combined with Triamterene.
Clindamycin Injection Clindamycin Injection The metabolism of Clindamycin can be decreased when combined with Rucaparib.
Secobarbital Secobarbital The metabolism of Rucaparib can be increased when combined with Secobarbital.
Desipramine Desipramine The metabolism of Desipramine can be decreased when combined with Rucaparib.
Amitriptyline Amitriptyline The metabolism of Amitriptyline can be decreased when combined with Rucaparib.
Imipramine Imipramine The metabolism of Imipramine can be decreased when combined with Rucaparib.
Quinidine Quinidine The serum concentration of Rucaparib can be increased when it is combined with Quinidine.
Procainamide Procainamide The metabolism of Procainamide can be decreased when combined with Rucaparib.
Isoniazid Isoniazid The metabolism of Rucaparib can be decreased when combined with Isoniazid.
Rifampin Rifampin The metabolism of Rifampicin can be increased when combined with Rucaparib.
Disopyramide Disopyramide The metabolism of Rucaparib can be decreased when combined with Disopyramide.
Valproic Acid Valproic Acid The metabolism of Valproic acid can be decreased when combined with Rucaparib.
Tamoxifen Tamoxifen The metabolism of Tamoxifen can be decreased when combined with Rucaparib.
Levothyroxine Levothyroxine The metabolism of Levothyroxine can be decreased when combined with Rucaparib.
Liothyronine Liothyronine The metabolism of Liothyronine can be decreased when combined with Rucaparib.
Methimazole Methimazole The metabolism of Rucaparib can be decreased when combined with Methimazole.
Chlorpropamide Chlorpropamide The metabolism of Chlorpropamide can be decreased when combined with Rucaparib.
Tolbutamide Tolbutamide The metabolism of Tolbutamide can be decreased when combined with Rucaparib.
Tolazamide Tolazamide The metabolism of Tolazamide can be decreased when combined with Rucaparib.
Dextromethorphan Dextromethorphan The metabolism of Dextromethorphan can be decreased when combined with Rucaparib.
Dinoprostone Dinoprostone The excretion of Dinoprostone can be decreased when combined with Rucaparib.
Cyclobenzaprine Cyclobenzaprine The metabolism of Cyclobenzaprine can be increased when combined with Rucaparib.
Niacin Niacin The metabolism of Rucaparib can be decreased when combined with Niacin.
Clemastine Clemastine The metabolism of Rucaparib can be decreased when combined with Clemastine.
Chlorpheniramine Chlorpheniramine The metabolism of Chlorpheniramine can be decreased when combined with Rucaparib.
Meclizine Meclizine The metabolism of Meclizine can be decreased when combined with Rucaparib.
Hydrochlorothiazide Hydrochlorothiazide The excretion of Hydrochlorothiazide can be decreased when combined with Rucaparib.
Chlorzoxazone Chlorzoxazone The metabolism of Rucaparib can be decreased when combined with Chlorzoxazone.
Carisoprodol Carisoprodol The metabolism of Carisoprodol can be decreased when combined with Rucaparib.
Folic Acid Folic Acid Rucaparib may decrease the excretion rate of Folic acid which could result in a higher serum level.
Disulfiram Disulfiram The metabolism of Rucaparib can be decreased when combined with Disulfiram.
Propranolol (Cardiovascular) Propranolol (Cardiovascular) The serum concentration of Propranolol can be increased when it is combined with Rucaparib.
Minoxidil Minoxidil The metabolism of Minoxidil can be decreased when combined with Rucaparib.
Nortriptyline Nortriptyline The metabolism of Nortriptyline can be decreased when combined with Rucaparib.
Mercaptopurine Mercaptopurine The excretion of Mercaptopurine can be decreased when combined with Rucaparib.
Nadolol Nadolol The metabolism of Nadolol can be decreased when combined with Rucaparib.
Allopurinol Allopurinol Rucaparib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Clomiphene Clomiphene The serum concentration of Clomifene can be increased when it is combined with Rucaparib.
Fluorouracil Injection Fluorouracil Injection The metabolism of Fluorouracil can be decreased when combined with Rucaparib.
Colchicine Colchicine The metabolism of Colchicine can be decreased when combined with Rucaparib.
Cefaclor Cefaclor The excretion of Cefaclor can be decreased when combined with Rucaparib.
Cefazolin Injection Cefazolin Injection The excretion of Cefazolin can be decreased when combined with Rucaparib.
Cephalexin Cephalexin The excretion of Cephalexin can be decreased when combined with Rucaparib.
Dacarbazine Dacarbazine The metabolism of Rucaparib can be increased when combined with Dacarbazine.
Ketoconazole Ketoconazole The metabolism of Rucaparib can be decreased when combined with Ketoconazole.
Thiotepa Injection Thiotepa Injection The metabolism of Thiotepa can be decreased when combined with Rucaparib.
Vincristine Injection Vincristine Injection The excretion of Vincristine can be decreased when combined with Rucaparib.
Captopril Captopril The excretion of Captopril can be decreased when combined with Rucaparib.
Vinblastine Vinblastine The metabolism of Rucaparib can be decreased when combined with Vinblastine.
Metoprolol Metoprolol The metabolism of Metoprolol can be decreased when combined with Rucaparib.
Hydroxyzine Hydroxyzine The metabolism of Rucaparib can be decreased when combined with Hydroxyzine.
Thiothixene Thiothixene The metabolism of Rucaparib can be decreased when combined with Thiothixene.
Aspirin Aspirin The metabolism of Acetylsalicylic acid can be decreased when combined with Rucaparib.
Alprazolam Alprazolam The metabolism of Alprazolam can be decreased when combined with Rucaparib.
Triazolam Triazolam The metabolism of Triazolam can be decreased when combined with Rucaparib.
Trimethoprim Trimethoprim The metabolism of Trimethoprim can be decreased when combined with Rucaparib.
Diltiazem Diltiazem The metabolism of Diltiazem can be decreased when combined with Rucaparib.
Nifedipine Nifedipine The metabolism of Rucaparib can be decreased when combined with Nifedipine.
Timolol Timolol The metabolism of Timolol can be decreased when combined with Rucaparib.
Verapamil Verapamil The metabolism of Verapamil can be decreased when combined with Rucaparib.
Atenolol Atenolol The metabolism of Atenolol can be decreased when combined with Rucaparib.
Pindolol Pindolol The metabolism of Pindolol can be decreased when combined with Rucaparib.
Piroxicam Piroxicam The metabolism of Piroxicam can be decreased when combined with Rucaparib.
Bumetanide Bumetanide The excretion of Bumetanide can be decreased when combined with Rucaparib.
Streptozocin Streptozocin The metabolism of Rucaparib can be increased when combined with Streptozocin.
Etoposide Etoposide The serum concentration of Etoposide can be increased when it is combined with Rucaparib.
Glyburide Glyburide Rucaparib may decrease the excretion rate of Glyburide which could result in a higher serum level.
Glipizide Glipizide The metabolism of Glipizide can be decreased when combined with Rucaparib.
Nafcillin Injection Nafcillin Injection The metabolism of Rucaparib can be increased when combined with Nafcillin.
Pentoxifylline Pentoxifylline The metabolism of Rucaparib can be decreased when combined with Pentoxifylline.
Pentamidine Injection Pentamidine Injection The metabolism of Pentamidine can be decreased when combined with Rucaparib.
Labetalol Labetalol The metabolism of Rucaparib can be decreased when combined with Labetalol.
Gemfibrozil Gemfibrozil The metabolism of Gemfibrozil can be decreased when combined with Rucaparib.
Guanabenz Guanabenz The metabolism of Rucaparib can be decreased when combined with Guanabenz.
Dipivefrin Ophthalmic Dipivefrin Ophthalmic The excretion of Adefovir dipivoxil can be decreased when combined with Rucaparib.
Ketoprofen Ketoprofen The metabolism of Ketoprofen can be decreased when combined with Rucaparib.
Pimozide Pimozide The metabolism of Pimozide can be decreased when combined with Rucaparib.
Enalapril Enalapril The excretion of Enalapril can be decreased when combined with Rucaparib.
Flurbiprofen Flurbiprofen The metabolism of Flurbiprofen can be decreased when combined with Rucaparib.
Amiodarone Amiodarone The metabolism of Rucaparib can be decreased when combined with Amiodarone.
Buspirone Buspirone The metabolism of Buspirone can be decreased when combined with Rucaparib.
Lovastatin Lovastatin The metabolism of Lovastatin can be decreased when combined with Rucaparib.
Ciprofloxacin Ciprofloxacin The metabolism of Rucaparib can be decreased when combined with Ciprofloxacin.
Diclofenac Diclofenac The metabolism of Diclofenac can be decreased when combined with Rucaparib.
Fluoxetine Fluoxetine The serum concentration of Rucaparib can be increased when it is combined with Fluoxetine.
Interferon Alfa-2b Injection Interferon Alfa-2b Injection The metabolism of Rucaparib can be decreased when combined with Interferon alfa-2b.
Clozapine Clozapine The metabolism of Rucaparib can be decreased when combined with Clozapine.
Idarubicin Idarubicin The metabolism of Idarubicin can be decreased when combined with Rucaparib.
Ofloxacin Ofloxacin The metabolism of Rucaparib can be decreased when combined with Ofloxacin.
Didanosine Didanosine The excretion of Didanosine can be decreased when combined with Rucaparib.
Clarithromycin Clarithromycin The serum concentration of Rucaparib can be increased when it is combined with Clarithromycin.
Etodolac Etodolac The metabolism of Etodolac can be decreased when combined with Rucaparib.
Felodipine Felodipine The metabolism of Felodipine can be decreased when combined with Rucaparib.
Nabumetone Nabumetone The metabolism of Rucaparib can be decreased when combined with Nabumetone.
Pravastatin Pravastatin The serum concentration of Pravastatin can be increased when it is combined with Rucaparib.
Quinapril Quinapril The excretion of Quinapril can be decreased when combined with Rucaparib.
Simvastatin Simvastatin The metabolism of Simvastatin can be decreased when combined with Rucaparib.
Epoetin Alfa, Injection Epoetin Alfa, Injection The risk or severity of Thrombosis can be increased when Erythropoietin is combined with Rucaparib.
Teniposide Injection Teniposide Injection The metabolism of Teniposide can be decreased when combined with Rucaparib.
Itraconazole Itraconazole The serum concentration of Rucaparib can be increased when it is combined with Itraconazole.
Sotalol Sotalol The metabolism of Sotalol can be decreased when combined with Rucaparib.
Bisoprolol Bisoprolol The serum concentration of Rucaparib can be increased when it is combined with Bisoprolol.
Zolpidem Zolpidem The metabolism of Zolpidem can be decreased when combined with Rucaparib.
Doxazosin Doxazosin The metabolism of Rucaparib can be decreased when combined with Doxazosin.
Omeprazole Omeprazole Omeprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Cisapride Cisapride The metabolism of Rucaparib can be decreased when combined with Cisapride.
Fluvastatin Fluvastatin The metabolism of Fluvastatin can be decreased when combined with Rucaparib.
Venlafaxine Venlafaxine The metabolism of Venlafaxine can be decreased when combined with Rucaparib.
Stavudine Stavudine The excretion of Stavudine can be decreased when combined with Rucaparib.
Famciclovir Famciclovir The metabolism of Rucaparib can be decreased when combined with Famciclovir.
Fluvoxamine Fluvoxamine The metabolism of Rucaparib can be decreased when combined with Fluvoxamine.
Nefazodone Nefazodone The metabolism of Rucaparib can be decreased when combined with Nefazodone.
Lamotrigine Lamotrigine The metabolism of Lamotrigine can be decreased when combined with Rucaparib.
Losartan Losartan The metabolism of Losartan can be decreased when combined with Rucaparib.
Valacyclovir Valacyclovir The excretion of Valaciclovir can be decreased when combined with Rucaparib.
Tramadol Tramadol The metabolism of Tramadol can be decreased when combined with Rucaparib.
Vinorelbine Injection Vinorelbine Injection The metabolism of Rucaparib can be decreased when combined with Vinorelbine.
Lansoprazole Lansoprazole Lansoprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Alprostadil Urogenital Alprostadil Urogenital The excretion of Alprostadil can be decreased when combined with Rucaparib.
Ifosfamide Injection Ifosfamide Injection The metabolism of Ifosfamide can be decreased when combined with Rucaparib.
Nicardipine Nicardipine The metabolism of Rucaparib can be decreased when combined with Nicardipine.
Bupropion Bupropion The metabolism of Rucaparib can be decreased when combined with Bupropion.
Ticlopidine Ticlopidine The metabolism of Rucaparib can be decreased when combined with Ticlopidine.
Saquinavir Saquinavir Saquinavir may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Metformin Metformin The excretion of Metformin can be decreased when combined with Rucaparib.
Nisoldipine Nisoldipine The metabolism of Nisoldipine can be decreased when combined with Rucaparib.
Lamivudine Lamivudine Rucaparib may decrease the excretion rate of Lamivudine which could result in a higher serum level.
Riluzole Riluzole Rucaparib may decrease the excretion rate of Riluzole which could result in a higher serum level.
Glimepiride Glimepiride The metabolism of Glimepiride can be decreased when combined with Rucaparib.
Anastrozole Anastrozole The metabolism of Anastrozole can be decreased when combined with Rucaparib.
Gemcitabine Injection Gemcitabine Injection The serum concentration of Gemcitabine can be increased when it is combined with Rucaparib.
Indinavir Indinavir The metabolism of Indinavir can be decreased when combined with Rucaparib.
Ritonavir Ritonavir The serum concentration of Rucaparib can be increased when it is combined with Ritonavir.
Docetaxel Injection Docetaxel Injection The metabolism of Docetaxel can be decreased when combined with Rucaparib.
Cidofovir Injection Cidofovir Injection The excretion of Cidofovir can be decreased when combined with Rucaparib.
Clomipramine Clomipramine The metabolism of Clomipramine can be decreased when combined with Rucaparib.
Zafirlukast Zafirlukast The metabolism of Rucaparib can be decreased when combined with Zafirlukast.
Mirtazapine Mirtazapine The metabolism of Rucaparib can be decreased when combined with Mirtazapine.
Zileuton Zileuton The metabolism of Rucaparib can be decreased when combined with Zileuton.
Valsartan Valsartan The metabolism of Valsartan can be decreased when combined with Rucaparib.
Insulin Lispro Injection Insulin Lispro Injection The metabolism of Rucaparib can be increased when combined with Insulin lispro.
Pramipexole Pramipexole The risk or severity of adverse effects can be increased when Rucaparib is combined with Pramipexole.
Donepezil Donepezil The metabolism of Donepezil can be decreased when combined with Rucaparib.
Nelfinavir Nelfinavir The metabolism of Nelfinavir can be decreased when combined with Rucaparib.
Fexofenadine Fexofenadine The serum concentration of Rucaparib can be increased when it is combined with Fexofenadine.
Azithromycin Azithromycin The metabolism of Azithromycin can be decreased when combined with Rucaparib.
Carvedilol Carvedilol The metabolism of Carvedilol can be decreased when combined with Rucaparib.
Flutamide Flutamide The metabolism of Rucaparib can be decreased when combined with Flutamide.
Selegiline Selegiline The metabolism of Rucaparib can be decreased when combined with Selegiline.
Bicalutamide Bicalutamide The metabolism of Rucaparib can be decreased when combined with Bicalutamide.
Sertraline Sertraline The metabolism of Sertraline can be decreased when combined with Rucaparib.
Propafenone Propafenone The metabolism of Rucaparib can be decreased when combined with Propafenone.
Raloxifene Raloxifene The metabolism of Raloxifene can be decreased when combined with Rucaparib.
Irbesartan Irbesartan The metabolism of Irbesartan can be decreased when combined with Rucaparib.
Tamsulosin Tamsulosin The metabolism of Tamsulosin can be decreased when combined with Rucaparib.
Ropinirole Ropinirole The risk or severity of adverse effects can be increased when Rucaparib is combined with Ropinirole.
Finasteride Finasteride The metabolism of Finasteride can be decreased when combined with Rucaparib.
Quetiapine Quetiapine The metabolism of Quetiapine can be decreased when combined with Rucaparib.
Paroxetine Paroxetine The metabolism of Rucaparib can be decreased when combined with Paroxetine.
Citalopram Citalopram The risk or severity of QTc prolongation can be increased when Rucaparib is combined with Citalopram.
Capecitabine Capecitabine The metabolism of Capecitabine can be decreased when combined with Rucaparib.
Efavirenz Efavirenz The metabolism of Rucaparib can be decreased when combined with Efavirenz.
Abacavir Abacavir The metabolism of Abacavir can be decreased when combined with Rucaparib.
Sildenafil Sildenafil The metabolism of Sildenafil can be decreased when combined with Rucaparib.
Pioglitazone Pioglitazone The metabolism of Pioglitazone can be decreased when combined with Rucaparib.
Celecoxib Celecoxib The metabolism of Celecoxib can be decreased when combined with Rucaparib.
Rosiglitazone Rosiglitazone The metabolism of Rucaparib can be decreased when combined with Rosiglitazone.
Tolterodine Tolterodine The metabolism of Tolterodine can be decreased when combined with Rucaparib.
Thalidomide Thalidomide The metabolism of Thalidomide can be decreased when combined with Rucaparib.
Oseltamivir Oseltamivir The excretion of Oseltamivir can be decreased when combined with Rucaparib.
Nateglinide Nateglinide The metabolism of Nateglinide can be decreased when combined with Rucaparib.
Galantamine Galantamine The metabolism of Galantamine can be decreased when combined with Rucaparib.
Rabeprazole Rabeprazole Rabeprazole may decrease the excretion rate of Rucaparib which could result in a higher serum level.
Terbinafine Terbinafine The metabolism of Rucaparib can be decreased when combined with Terbinafine.

Content provided by: AHFS® Patient Medication Information™. © Copyright, 2021. The American Society of Health-System Pharmacists