Vorinostat

41 interactions 3 explained in plain English
Also sold as: Zolinza Zolinza®
About Vorinostat

Vorinostat is used to treat cutaneous T-cell lymphoma (CTCL, a type of cancer) in people whose disease has not improved, has gotten worse, or has come back after taking other medications. Vorinostat is in a class of medications called histone deacetylase (HDAC) inhibitors. It works by killing or stopping the growth of… Read the full Vorinostat drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levofloxacin Injection Goserelin Implant Ivabradine Amisulpride Injection Oxaliplatin Injection Hydroxychloroquine
41 Major
All (41) Major (41)

Major

Vorinostat Sertraline Explained An increased risk of QT interval prolongation Details Vorinostat Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Vorinostat Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Vorinostat Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Vorinostat Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Vorinostat Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Vorinostat Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Vorinostat Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Vorinostat Azithromycin AzaSite An increased risk of QT interval prolongation and torsade de pointes Details Vorinostat Anagrelide Agrylin Increased risk of QT interval prolongation Details Vorinostat Bedaquiline Sirturo Increased risk of QT interval prolongation Details Vorinostat Chloroquine Aralen® Increased risk of QT-interval prolongation Details Vorinostat Dasatinib Phyrago An increased risk of QT interval prolongation Details Vorinostat Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Vorinostat Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Vorinostat Dofetilide Tikosyn An increased risk of QT interval prolongation Details Vorinostat Encorafenib Braftovi Increased risk of QT interval prolongation Details Vorinostat Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Vorinostat Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Vorinostat Fostemsavir Rukobia Increased risk of torsade de pointes Details Vorinostat Glasdegib Daurismo Increased risk of QT interval prolongation Details Vorinostat Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Vorinostat Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Vorinostat Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Vorinostat Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Vorinostat Ivabradine Corlanor Increased risk of QT prolongation Details Vorinostat Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Vorinostat Lefamulin Xenleta Increased risk of QT interval prolongation Details Vorinostat Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Vorinostat Levofloxacin Levaquin Increased risk of QT interval prolongation Details Vorinostat Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Vorinostat Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Vorinostat Metronidazole Flagyl An increased risk of QT interval prolongation Details Vorinostat Metronidazole Injection Flagyl An increased risk of QT interval prolongation Details Vorinostat Metronidazole Topical MetroCream® An increased risk of QT interval prolongation Details Vorinostat Metronidazole Vaginal MetroGel® Vaginal An increased risk of QT interval prolongation Details Vorinostat Moxifloxacin Avelox Increased risk of QT interval prolongation Details Vorinostat Moxifloxacin Injection Avelox Increased risk of QT interval prolongation Details Vorinostat Moxifloxacin Ophthalmic Moxeza® Increased risk of QT interval prolongation Details Vorinostat Olodaterol Oral Inhalation Striverdi An increased risk of QT interval prolongation and an increased risk of ventricular arrhythmias Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.