Dabigatran

284 interactions 383 cited references

Also sold as: Pradaxa®

About Dabigatran

Dabigatran is a direct thrombin inhibitor anticoagulant used to treat blood clots and prevent strokes in patients with irregular heartbeats. Read the full Dabigatran drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Defibrotide Zanubrutinib Ensitrelvir Enoxaparin Enasidenib

2 Contraindicated 253 Major 29 Moderate

All (284) Contraindicated (2) Major (253) Moderate (29)

Contraindicated

Dabigatran Defibrotide Increased risk of bleeding Details Dabigatran Levoketoconazole Recorlev Increased CYP3A4/P-gp substrate exposure Details

Major

Dabigatran Abciximab An increased risk of bleeding Details Dabigatran Abiraterone Acetate Abirtega Increased dabigatran etexilate exposure Details Dabigatran Abiraterone Acetate, Micronized Abirtega Increased dabigatran etexilate exposure Details Dabigatran Abrocitinib Cibinqo Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Aceclofenac An increased risk of bleeding Details Dabigatran Acemetacin An increased risk of bleeding Details Dabigatran Acenocoumarol An increased risk of bleeding Details Dabigatran Adagrasib Krazati Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Alipogene Tiparvovec An increased risk of bleeding Details Dabigatran Alogliptin Nesina Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Alteplase, Recombinant Activase An increased risk of bleeding Details Dabigatran Amiodarone Nexterone Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Amtolmetin Guacil An increased risk of bleeding Details Dabigatran Anagrelide Agrylin Increased risk of bleeding Details Dabigatran Anistreplase An increased risk of bleeding Details Dabigatran Apalutamide Erleada Reduced dabigatran exposure, reduced efficacy of dabigatran and an increased risk of thrombosis Details Dabigatran Apixaban Eliquis An increased risk of bleeding and can cause serious, potentially fatal bleeding Details Dabigatran Ardeparin An increased risk of bleeding Details Dabigatran Argatroban An increased risk of bleeding Details Dabigatran Aspirin Acuprin® Increased risk of bleeding Details Dabigatran Asunaprevir Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Atazanavir Reyataz Increased dabigatran etexilate exposure and an increased risk of bleeding Details Dabigatran Azithromycin AzaSite Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Bemiparin An increased risk of bleeding Details Dabigatran Berotralstat Orladeyo Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Betrixaban Bevyxxa® Increased risk of bleeding Details Dabigatran Bivalirudin Angiomax An increased risk of bleeding Details Dabigatran Boceprevir Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Bromfenac Bromsite An increased risk of bleeding Details Dabigatran Bufexamac An increased risk of bleeding Details Dabigatran Canagliflozin Invokana Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Cangrelor Kengreal Increased risk of bleeding Details Dabigatran Caplacizumab-Yhdp An increased risk of bleeding Details Dabigatran Capmatinib Tabrecta Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Captopril Capoten® Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Carbamazepine Carbatrol Reduced dabigatran exposure and reduced efficacy of dabigatran Details Dabigatran Carvedilol Coreg Increased dabigatran exposure and an increased risk of bleeding Details Dabigatran Celecoxib Celebrex An increased risk of bleeding Details

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