Dabigatran

284 interactions 383 cited references
Also sold as: Pradaxa®
About Dabigatran

Dabigatran is a direct thrombin inhibitor anticoagulant used to treat blood clots and prevent strokes in patients with irregular heartbeats. Read the full Dabigatran drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Defibrotide Zanubrutinib Ensitrelvir Enoxaparin Enasidenib
2 Contraindicated 253 Major 29 Moderate
All (284) Contraindicated (2) Major (253) Moderate (29)

Moderate

Dabigatran Betamethasone Betavet Increased risk of gastrointestinal bleeding Details Dabigatran Curcumin Increased exposure of dabigatran and an increased risk of bleeding Details Dabigatran Darunavir Increased dabigatran etexilate exposure Details Dabigatran Dexamethasone Increased risk of gastrointestinal bleeding Details Dabigatran Duloxetine Altered anticoagulation effects, including increased risk of bleeding Details Dabigatran Echinacea Increased risk of bleeding Details Dabigatran Garlic An increased risk of bleeding Details Dabigatran Ginger An increased risk of bleeding Details Dabigatran Ginkgo Increased exposure of dabigatran and an increased risk of bleeding Details Dabigatran Ginseng An increased risk of bleeding Details Dabigatran Ginseng, American An increased risk of bleeding Details Dabigatran Ginseng, Chinese An increased risk of bleeding Details Dabigatran Horse Chestnut An increased risk of bleeding Details Dabigatran Hydrocortisone Ala-Cort Increased risk of gastrointestinal bleeding Details Dabigatran Icosapent Ethyl Vascepa An increased risk of bleeding Details Dabigatran Levacetylleucine Aqneursa Increased P-gp inhibitor exposure and an increased risk of P-gp substrate-related adverse reactions Details Dabigatran Levothyroxine Ermeza Increased response to oral anticoagulant therapy Details Dabigatran Lomitapide Increased P-gp substrate exposure Details Dabigatran Methylprednisolone Depo-Medrol Increased risk of gastrointestinal bleeding Details Dabigatran Omega-3-Acid Ethyl Esters Lovaza An increased risk of bleeding Details Dabigatran Omega-3-Carboxylic Acids An increased risk of bleeding Details Dabigatran Posaconazole Noxafil Increased exposure of dabigatran etexilate Details Dabigatran Prednisolone Flo-Pred® Increased risk of gastrointestinal bleeding Details Dabigatran Prednisone Deltasone Increased risk of gastrointestinal bleeding Details Dabigatran Sodium Zirconium Cyclosilicate Lokelma Decreased dabigatran exposure Details Dabigatran Sparsentan Filspari Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse effects Details Dabigatran Tibolone Increased risk of bleeding Details Dabigatran Triamcinolone Aller-Cort Increased risk of gastrointestinal bleeding Details Dabigatran Valerian Increased risk of bleeding Details

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