Nitroglycerin Transdermal Patch

15 interactions 500 cited references
Also sold as: Minitran® Patch Nitro-Dur Nitro-Dur® Patch
About Nitroglycerin Transdermal Patch

Nitroglycerin transdermal patches are used to prevent episodes of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Nitroglycerin transdermal patches can only be used to prevent attacks of angina; they cannot be used to treat an attack of ang… Read the full Nitroglycerin Transdermal Patch drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Avanafil Riociguat Sildenafil Tadalafil Vardenafil Alteplase, Recombinant
5 Contraindicated 4 Major 6 Moderate
All (15) Contraindicated (5) Major (4) Moderate (6)

Contraindicated

Nitroglycerin Transdermal Patch Avanafil Stendra Potentiation of hypotensive effects Details Nitroglycerin Transdermal Patch Riociguat Adempas Increased risk of hypotension Details Nitroglycerin Transdermal Patch Sildenafil Liqrev Potentiation of hypotensive effects Details Nitroglycerin Transdermal Patch Tadalafil Adcirca Increased hypotensive effects of nitrates Details Nitroglycerin Transdermal Patch Vardenafil Levitra Potentiation of hypotensive effects Details

Major

Nitroglycerin Transdermal Patch Alteplase, Recombinant Activase Less coronary artery reperfusion, longer time to reperfusion, and more coronary artery reocclusion Details Nitroglycerin Transdermal Patch Articaine An increased risk of methemoglobinemia Details Nitroglycerin Transdermal Patch Heparin A decrease in partial thromboplastin time Details Nitroglycerin Transdermal Patch Lidocaine Akten An increased risk of methemoglobinemia Details

Moderate

Nitroglycerin Transdermal Patch Acetylcysteine Acetadote Enhanced hypotension and nitroglycerin-induced headache Details Nitroglycerin Transdermal Patch Apomorphine Apokyn An increased risk of hypotension Details Nitroglycerin Transdermal Patch Aspirin Acuprin® An increase in nitroglycerin concentrations and additive platelet function depression Details Nitroglycerin Transdermal Patch Dihydroergotamine Brekiya Dihydroergotamine toxicity (peripheral ischemia, paresthesias, nausea, vomiting) Details Nitroglycerin Transdermal Patch Nitric Oxide An increased risk of methemoglobinemia Details Nitroglycerin Transdermal Patch Pancuronium An increase in pancuronium duration of action Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.