Nitroglycerin
Nitroglycerin is a nitrate vasodilator used across multiple forms and brands to relieve or prevent angina (chest pain), treat heart failure and high blood pressure in hospital settings, and ease pain from chronic anal fissure.
🧬 Where this information comes from Click to expand
The clinical label records used on this page are FDA-filed Structured Product Labeling (SPL) retrieved through openFDA. We identified 35 clinical label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. Forms, routes, brands, labelers, strengths, and NDC product-record counts are built separately from matching FDA National Drug Code Directory records. The linked DailyMed document is a representative official source for verification, not the page’s only clinical source. View the linked label on DailyMed →
📖 Nitroglycerin: Patient Information Guide
A plain-language walkthrough of Nitroglycerin — what it treats, how it works, how it’s taken, side effects, warnings and interactions. Tap any section to expand it.
🎯What it's used for▾
Nitroglycerin is used across several forms and settings — the right form depends on whether the goal is to stop an acute attack or prevent one from happening.
- Sublingual tablets and lingual sprays (Nitroglycerin Lingual Spray, Nitrolingual): acute relief or short-term prevention of angina attacks from coronary artery disease
- Nitro-Time extended-release capsules (oral): prevention of angina from coronary artery disease — not for stopping an active attack
- Transdermal patches (Nitro-Dur, Nitroglycerin Transdermal Infusion System, Nitroglycerin Transdermal System): prevention of angina from coronary artery disease — not for stopping an active attack
- Rectiv rectal ointment / Nitroglycerin rectal ointment 0.4%: treatment of moderate to severe pain from chronic anal fissure
- Nitroglycerin Injection / Nitroglycerin in Dextrose (IV, hospital use only): treatment of high blood pressure around surgery; control of heart failure during a heart attack; treatment of angina not responding to sublingual nitroglycerin and beta-blockers; controlled low blood pressure during surgery
⚙️How it works▾
Nitroglycerin releases nitric oxide (NO) inside the body. NO activates an enzyme called guanylate cyclase, which raises levels of a chemical messenger (cyclic GMP) that tells smooth muscle cells in blood vessel walls to relax. When vessels relax and widen, blood pools more in the veins (reducing the load returning to the heart) and arteries offer less resistance — the heart works less, uses less oxygen, and chest pain eases.
With ongoing daily use, the body can develop tolerance — the vessels stop responding as strongly. That's why patch and capsule regimens require a daily drug-free interval of at least 10–12 hours.
💊How it's taken▾
Nitroglycerin comes in several forms, each with its own schedule — do not mix instructions between them.
- Sublingual tablets / lingual sprays: taken or sprayed at the onset of chest pain, may be repeated every 5 minutes up to 3 times; if pain continues, seek emergency care. May also be used 5–10 minutes before an activity likely to trigger angina.
- Nitro-Time capsules and transdermal patches: taken on a regular daily schedule that always includes a nitrate-free break (typically 10–12 hours overnight) to prevent tolerance. Patches are worn 12–14 hours, then removed.
- Rectiv / rectal ointment: applied every 12 hours for up to 3 weeks.
- IV forms: administered only by healthcare providers in a clinical setting using an infusion pump.
🤒Side effects — in detail▾
Most side effects are directly related to nitroglycerin's blood vessel–widening action.
- Headache — the most common; often severe at first but usually improves with continued use
- Lightheadedness or dizziness
- Low blood pressure (hypotension), especially when standing
- Flushing (skin redness and warmth)
- Nausea or vomiting
- Slightly faster heartbeat
- Shortness of breath
Seek emergency help right away if you faint, develop severe or persistent low blood pressure, notice bluish or chocolate-brown skin (a sign of a rare blood oxygen problem called methemoglobinemia), or experience an allergic reaction such as hives or swelling.
⚠️Warnings & precautions▾
- Severe low blood pressure: Even normal doses can cause a dangerous drop in blood pressure, especially if you stand quickly, are dehydrated, or already have low blood pressure. Sit or lie down when using fast-acting forms. Symptoms include dizziness, nausea, pale sweaty skin, and fainting.
- PDE-5 inhibitor interaction: Combining nitroglycerin with ED drugs (sildenafil, tadalafil, vardenafil, avanafil) or the lung drug riociguat can cause a severe, potentially life-threatening drop in blood pressure. This combination is contraindicated.
- Tolerance: Continuous use without a daily drug-free break leads to the drug losing its effect completely within 24 hours. Always follow the prescribed patch-off or nitrate-free interval.
- Hypertrophic obstructive cardiomyopathy: Nitroglycerin may worsen chest pain in people with this particular heart muscle condition.
- Increased brain pressure: Nitroglycerin can raise pressure inside the skull and must not be used by people with cerebral hemorrhage or traumatic brain injury.
🔀What it interacts with▾
Nitroglycerin has several important drug interactions that can be dangerous.
- PDE-5 inhibitors (sildenafil, tadalafil, vardenafil, avanafil) — severely amplify blood pressure lowering; combination is contraindicated
- Soluble guanylate cyclase stimulators (riociguat) — causes dangerous hypotension; combination is contraindicated
- Ergotamine / dihydroergotamine — nitroglycerin raises ergotamine levels, which can itself trigger angina; avoid or monitor closely
- High-dose aspirin (1,000 mg) — increases nitroglycerin levels and may strengthen its blood pressure–lowering effect
- Tissue-type plasminogen activator (t-PA) — IV nitroglycerin lowers t-PA levels and reduces its clot-dissolving ability
This is not a complete list of interactions. Always talk with your doctor or pharmacist before starting, stopping, or changing any medication.
📋Before taking it▾
- Do not take if you use PDE-5 inhibitor medications for ED or pulmonary hypertension (sildenafil, tadalafil, vardenafil, avanafil) or the drug riociguat
- Do not take if you have severe anemia — nitroglycerin can worsen it by affecting hemoglobin
- Do not take if you have increased intracranial (brain) pressure, such as from a head injury or brain bleed
- Do not take in acute circulatory failure or shock
- Tell your prescriber if you have hypertrophic obstructive cardiomyopathy — nitroglycerin may worsen your angina
- Tell your prescriber if you are pregnant — human data are very limited; animal studies showed no harm but human risk is not fully known
- Tell your prescriber if you are breastfeeding — it is not known whether nitroglycerin passes into breast milk
- Children: safety and effectiveness have not been established
- Older adults: more sensitive to blood pressure effects; prescribers typically start at the lower end of the dose range
🚑If you take too much▾
Too much nitroglycerin overwhelms its blood pressure–lowering action, leading to severe low blood pressure, throbbing headache, confusion, rapid heartbeat, nausea, vomiting, fainting, and in extreme cases, seizures or loss of consciousness. There is no specific antidote; treatment focuses on raising blood pressure — often by lying down with legs elevated and, in severe cases, IV fluids. A rare but serious complication of very large doses is methemoglobinemia (a condition where hemoglobin can no longer carry oxygen properly), which is treated with methylene blue administered by a healthcare provider.
📡Pharmacodynamics — effects in the body▾
Nitroglycerin's main action is relaxing smooth muscle in blood vessel walls, with the strongest effect on veins. This widens large veins, allowing blood to pool in the limbs, which reduces the amount returning to the heart and lowers the filling pressure the heart must overcome (called preload). It also relaxes arteries, lowering the resistance the heart pumps against (afterload). Both effects reduce the heart's oxygen demand. Blood pressure — systolic, diastolic, and mean — typically falls with therapeutic doses, and heart rate may rise slightly as the body compensates. After sublingual administration, the vasodilatory effect begins within 1–3 minutes, peaks by 5 minutes, and lasts at least 25 minutes.
🔬Pharmacokinetics — how your body processes it▾
Nitroglycerin is absorbed very rapidly when given under the tongue, reaching peak blood levels in about 6–7 minutes. It is broken down quickly — mainly in the liver, but also in red blood cells and blood vessel walls — with a short half-life of only 2 to 3 minutes, so it clears fast. The body produces active breakdown products (dinitroglycerin metabolites) that last longer (half-lives of 32–36 minutes) and contribute to the drug's sustained effect. About 60% of nitroglycerin in the blood is bound to proteins. Because the body processes nitroglycerin so rapidly, continuous 24-hour exposure leads to tolerance; a daily drug-free period is essential for patch and capsule formulations.
📦How to store it▾
Store at 20°C to 25°C (68°F to 77°F) .
📄 Written from Nitroglycerin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Every point is grounded in that labeling — nothing is invented. How we use AI →
🩺 Pharmacist Counseling Corner
Quick, plain-English answers to the questions patients ask most about Nitroglycerin — the kind of thing our pharmacy team would talk through with you at the counter.
What's the difference between nitroglycerin for chest pain and the kind used for anal fissure pain? ▾
Can I use nitroglycerin if I take sildenafil (Viagra) or tadalafil (Cialis)? ▾
I got a terrible headache after taking nitroglycerin — is that normal? ▾
How do I use the sublingual tablet correctly during a chest pain attack? ▾
Why do I need to take the patch off every day? Can't I just leave it on? ▾
Is nitroglycerin safe to use if I'm pregnant or breastfeeding? ▾
Is Nitroglycerin available over the counter? ▾
When was Nitroglycerin first available? ▾
Who makes Nitroglycerin? ▾
💬 Answers drafted from Nitroglycerin’s FDA-approved label information, summarized in plain language with AI, and reviewed by our pharmacy team before publication. Grounded in that labeling — nothing is made up. How we use AI →
🧰 Keep exploring
💊 How Nitroglycerin comes
Nitroglycerin is available in 10 forms. Different forms and brands can have different approved uses, doses, schedules, and directions. Follow the instructions for your exact product, and do not switch forms without guidance from your prescriber or pharmacist.
Sublingual tablet
Skin patch
How this form is used
- Nitro-Dur and other transdermal nitroglycerin patches are used to prevent angina due to coronary artery disease
- Transdermal patches act too slowly to stop an acute angina attack — they are for prevention only
- Nitro-Dur and transdermal nitroglycerin patches are typically worn for 12–14 hours, then removed for a 10–12 hour nitrate-free period each day to prevent tolerance
- Apply the patch to skin as directed; follow your prescriber's schedule for when to put it on and take it off
Spray
How this form is used
- Nitroglycerin Lingual Spray and Nitrolingual Pumpspray are used for acute relief of angina attacks due to coronary artery disease
- Nitroglycerin Lingual Spray and Nitrolingual Pumpspray may also be used prophylactically before activities known to trigger angina
- Nitrolingual and Nitroglycerin Lingual Spray: spray one or two metered doses onto or under the tongue at the onset of an attack
- May repeat approximately every 5 minutes — no more than three sprays in a 15-minute period
- If chest pain continues after three sprays, seek emergency medical attention immediately
- May be used 5–10 minutes before activities likely to trigger an attack
Other oral form
Show 5 more strengths Show fewer strengths
Injection
How this form is used
- Nitroglycerin Injection and Nitroglycerin in Dextrose are used to treat high blood pressure around the time of surgery (peri-operative hypertension)
- Nitroglycerin Injection and Nitroglycerin in Dextrose are used to control heart failure in the setting of a heart attack
- Used to treat angina that has not responded to sublingual nitroglycerin and beta-blockers
- Used to produce controlled low blood pressure during surgery (intraoperative hypotension)
- Nitroglycerin Injection is given intravenously in a hospital or clinical setting only, using an infusion pump
- Nitroglycerin Injection should be given through non-PVC (low-absorbing) tubing to ensure the correct dose is delivered
- Dose is determined individually by a healthcare provider based on patient response
Rectal topical
How this form is used
- Rectiv is used to treat moderate to severe pain from chronic anal fissure
- Nitroglycerin rectal ointment 0.4% is used to treat moderate to severe pain from chronic anal fissure
- Rectiv is applied intra-anally every 12 hours for up to 3 weeks using a finger covering (such as a finger cot, glove, or plastic wrap)
- Apply the ointment no further than the first finger joint inside the anal canal; if pain prevents this, apply to the outside of the anus
Capsule
How this form is used
- Nitro-Time is used to prevent angina due to coronary artery disease
- Nitro-Time is not fast enough to stop an angina attack already in progress
- Nitro-Time is taken orally on a schedule that includes a daily nitrate-free interval (typically 10–12 hours) to prevent tolerance
- Follow your prescriber's schedule carefully — do not take Nitro-Time around the clock
Topical cream, ointment or gel
Oral solution
Inhaler
📊 Nitroglycerin across the U.S. market
How Nitroglycerin appears in the FDA’s National Drug Code Directory — including its dosage forms, strengths, brand names, manufacturers, and FDA-listed product records. These are directory records, not sales or prescription volume.
FDA-listed product records by dose form (tablet variants merged) — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
Share of FDA-listed product records by manufacturer — FDA National Drug Code Directory. Record counts are not sales or prescription volume.
📈 How widely Nitroglycerin is used
A general measure of how commonly Nitroglycerin is prescribed, based on Medicaid — one of the largest public drug programs. The figure below is prescriptions filled in Q1–Q4 2025, summed across every form and brand of the drug.
Think of this as a proxy for how widely Nitroglycerin is used, drawn from freely available public data. Medicaid is just one program — these numbers don’t include Medicare, other government coverage, or commercial and cash-pay prescriptions, so real-world use is higher than what’s shown here.
How commonly is Nitroglycerin prescribed? Of the 1,594 medications we measure, Nitroglycerin ranks #308 by Medicaid prescriptions — more than 81% of them.
Utilization by Nitroglycerin product
Pick a product to see its own Medicaid numbers. Each chip is one clinical product — a specific strength & dosage form as defined by RxNorm — with brand-name and generic versions combined.
nitroglycerin 0.4 MG Sublingual Tablet Most dispensed
Summed across the 17 of 95 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198039
nitroglycerin 0.3 MG Sublingual Tablet
Summed across the 8 of 16 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198038
nitroglycerin 0.02 MG/MG Topical Ointment
Summed across the 3 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 242946
nitroglycerin 0.004 MG/MG Rectal Ointment
Summed across the 4 of 7 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1114466
24 HR nitroglycerin 0.2 MG/HR Transdermal System
Summed across the 2 of 11 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 486148
250 ML nitroglycerin 0.2 MG/ML Injection
Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 312004
250 ML nitroglycerin 0.1 MG/ML Injection
Summed across the 1 of 2 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1868562
24 HR nitroglycerin 0.1 MG/HR Transdermal System
Summed across the 1 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 861657
24 HR nitroglycerin 0.4 MG/HR Transdermal System
Summed across the 1 of 14 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 486152
10 ML nitroglycerin 5 MG/ML Injection
Summed across the 1 of 8 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 237205
nitroglycerin 0.4 MG/ACTUAT Mucosal Spray
Summed across the 5 of 20 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 705129
250 ML nitroglycerin 0.4 MG/ML Injection
Summed across the 1 of 1 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 1868494
24 HR nitroglycerin 0.6 MG/HR Transdermal System
Summed across the 1 of 9 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 486146
nitroglycerin 0.6 MG Sublingual Tablet
Summed across the 2 of 15 listed NDC products with Medicaid activity — every brand and generic of this exact strength & form. RxNorm 198040
Shares are of the Medicaid prescriptions shown here. Product grouping follows RxNorm (the National Library of Medicine’s drug terminology), so “one product” means one strength & dosage form regardless of manufacturer. Dollar figures are gross Medicaid reimbursement before mandatory rebates — rebates (often large, especially for brand-name drugs) are confidential, so actual net cost to Medicaid is lower than shown.
Source: Medicaid State Drug Utilization Data (CMS), aggregated by generic ingredient — summed across every NDC (all brands, strengths, salt forms and dosage forms) of Nitroglycerin, and across all states and both fee-for-service and managed-care claims. A general popularity signal; it excludes Medicare, commercial insurance and cash prescriptions, so it is not total U.S. use. Based on the 48 of 215 listed Nitroglycerin NDCs with Medicaid activity.
🔍 Compare Nitroglycerin products
A representative set of FDA-listed product records for Nitroglycerin — across manufacturers, strengths, and dosage forms, grouped by form with each product’s manufacturer and how the FDA approved it. The same medicine may be made and packaged by different companies, so a single drug can have many directory entries. (It’s also why a refill can look different — a new shape, color, or box — even though it contains the same medication.)
| Strength | Route | Manufacturer / Labeler | Category ⓘ | Details |
|---|---|---|---|---|
| 💊Capsule | ||||
| 9 mg | Oral | Major Pharmaceuticals | UNAPPROVED DRUG OTHER | Find on DailyMed ↗ |
| 2.5 mg | Oral | Time Cap Laboratories, Inc × 2 listings | UNAPPROVED DRUG OTHER | View NDC → |
| 6.5 mg | Oral | Time Cap Laboratories, Inc × 2 listings | UNAPPROVED DRUG OTHER | View NDC → |
| 9 mg | Oral | Time Cap Laboratories, Inc × 2 listings | UNAPPROVED DRUG OTHER | View NDC → |
| 💊Inhaler | ||||
| 400 mcg | Sublingual | Mist Pharmaceuticals, LLC | NDA | View NDC → |
| 💊Injection | ||||
| 5 mg/mL | Intravenous | American Regent, Inc. | ANDA | View NDC → |
| 10 mg/100 mL | Intravenous | Baxter Healthcare Company × 2 listings | NDA | View NDC → |
| 20 mg/100 mL | Intravenous | Baxter Healthcare Company × 2 listings | NDA | View NDC → |
| 40 mg/100 mL | Intravenous | Baxter Healthcare Company × 2 listings | NDA | View NDC → |
| 5 mg/mL | Intravenous | General Injectables and Vaccines, Inc. | ANDA | View NDC → |
| 5 mg/mL | Intravenous | Henry Schein, Inc. × 3 listings | ANDA | View NDC → |
| 5 mg/mL | Intravenous | HF Acquisition Co LLC, DBA HealthFirst × 2 listings | ANDA | View NDC → |
| 10 mg/100 mL | Intravenous | ProPharma Distribution | NDA | View NDC → |
| 5 mg/mL | Intravenous | Remedyrepack Inc. × 2 listings | ANDA | View NDC → |
| 💊Oral solution | ||||
| 1 kg/kg | — | Dipharma Francis Srl | BULK INGREDIENT | View NDC → |
| 3.65 kg/100 kg | — | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik | DRUG FOR FURTHER PROCESSING | View NDC → |
| 20 kg/100 kg | — | Dynamit Nobel GmbH Explosivstoff- und Systemtechnik | DRUG FOR FURTHER PROCESSING | View NDC → |
| 💊Other oral form | ||||
| 5 [hp_C]/5 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 6 [hp_C]/6 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 6 [hp_X] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 9 [hp_C]/9 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 12 [hp_C]/12 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 15 [hp_C]/15 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 30 [hp_C]/30 [hp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 200 [kp_C]/200 [kp_C] | Oral | Boiron × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 30 [hp_C]/mL | Oral | Natural Health Supply | UNAPPROVED HOMEOPATHIC | View NDC → |
| 30 [hp_C] | Oral | Washington Homeopathic Products × 2 listings | UNAPPROVED HOMEOPATHIC | View NDC → |
| 200 [hp_C] | Oral | Washington Homeopathic Products | UNAPPROVED HOMEOPATHIC | View NDC → |
| 💊Rectal topical | ||||
| 4 mg/g | Rectal | Allergan, Inc. × 4 listings | NDA | View NDC → |
| 4 mg/g | Rectal | Bryant Ranch Prepack | ANDA | View NDC → |
| 4 mg/g | Rectal | Cosette Pharmaceuticals, Inc. | ANDA | View NDC → |
| 4 mg/g | Rectal | Encube Ethicals, Inc. | ANDA | View NDC → |
| 4 mg/g | Rectal | Padagis Israel Pharmaceuticals Ltd × 2 listings | ANDA | View NDC → |
| 4 mg/g | Rectal | Solaris Pharma Corporation | ANDA | View NDC → |
| 4 mg/g | Rectal | Trupharma, LLC | ANDA | View NDC → |
| 💊Skin patch | ||||
| 20 mg | Transdermal | Dr. Reddy's Laboratories, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 40 mg | Transdermal | Dr. Reddy's Laboratories, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 80 mg | Transdermal | Dr. Reddy's Laboratories, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 120 mg | Transdermal | Dr. Reddy's Laboratories, Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 20 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 40 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 60 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 80 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 120 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| 160 mg | Transdermal | Ingenus Pharmaceuticals, LLC × 2 listings | NDA | View NDC → |
| NITROGLYCERIN 0.1 mg/h | Transdermal | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| NITROGLYCERIN 0.2 mg/h | Transdermal | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| NITROGLYCERIN 0.4 mg/h | Transdermal | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| NITROGLYCERIN 0.6 mg/h | Transdermal | Mylan Pharmaceuticals Inc. | ANDA | View NDC → |
| 0.1 mg/h | Transdermal | Zydus Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 0.2 mg/h | Transdermal | Zydus Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 0.4 mg/h | Transdermal | Zydus Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 0.6 mg/h | Transdermal | Zydus Pharmaceuticals USA Inc. | ANDA | View NDC → |
| 💊Spray | ||||
| 400 mcg | Oral | Allegis Pharmaceuticals, LLC × 2 listings | NDA AUTHORIZED GENERIC | View NDC → |
| 400 mcg | Oral | Allegis Pharmaceuticals, LLC × 3 listings | NDA | View NDC → |
| 400 mcg | Oral | HF Acquisition Co. LLC, DBA Health First × 2 listings | NDA | View NDC → |
| 400 mcg | Oral | HF Acquisition Co LLC, DBA HealthFirst × 5 listings | NDA | View NDC → |
| 400 mcg | Oral | HF Acquisition Co LLC, DBA HealthFirst × 4 listings | ANDA | View NDC → |
| 400 mcg | Oral | Independence Pharmaceuticals, Llc | NDA | View NDC → |
| 400 mcg | Oral | NuCare Pharmaceuticals,Inc. | ANDA | Find on DailyMed ↗ |
| 400 mcg | Oral | Padagis Israel Pharmaceuticals Ltd × 2 listings | ANDA | View NDC → |
| 400 mcg | Oral | Prasco Laboratories | NDA AUTHORIZED GENERIC | View NDC → |
| 💊Sublingual tablet | ||||
| 0.4 mg | Sublingual | A-S Medication Solutions × 6 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | A-S Medication Solutions × 4 listings | NDA | View NDC → |
| 0.3 mg | Sublingual | Advagen Pharma Ltd × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Advagen Pharma Ltd × 2 listings | ANDA | View NDC → |
| 0.6 mg | Sublingual | Advagen Pharma Ltd × 2 listings | ANDA | View NDC → |
| 400 mcg | Sublingual | Allegis Pharmaceuticals, Inc. | NDA | View NDC → |
| 0.3 mg | Sublingual | Alvogen Inc. | ANDA | View NDC → |
| 0.4 mg | Sublingual | Alvogen Inc. | ANDA | View NDC → |
| 0.6 mg | Sublingual | Alvogen Inc. | ANDA | View NDC → |
| 0.3 mg | Sublingual | Aurobindo Pharma Limited | ANDA | View NDC → |
| 0.4 mg | Sublingual | Aurobindo Pharma Limited | ANDA | View NDC → |
| 0.6 mg | Sublingual | Aurobindo Pharma Limited | ANDA | View NDC → |
| 0.3 mg | Sublingual | Bryant Ranch Prepack | ANDA | View NDC → |
| 0.4 mg | Sublingual | Bryant Ranch Prepack × 3 listings | ANDA | View NDC → |
| 0.3 mg | Sublingual | DASH Pharmaceuticals LLC | ANDA | View NDC → |
| 0.4 mg | Sublingual | DASH Pharmaceuticals LLC | ANDA | View NDC → |
| 0.6 mg | Sublingual | DASH Pharmaceuticals LLC | ANDA | View NDC → |
| 0.3 mg | Sublingual | Dr. Reddys Laboratories Inc × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Dr. Reddys Laboratories Inc × 2 listings | ANDA | View NDC → |
| 0.6 mg | Sublingual | Dr. Reddys Laboratories Inc × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | General Injectables & Vaccines, Inc | NDA | View NDC → |
| 0.3 mg | Sublingual | Glenmark Pharmaceuticals Inc., USA × 3 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Glenmark Pharmaceuticals Inc., USA × 3 listings | ANDA | View NDC → |
| 0.6 mg | Sublingual | Glenmark Pharmaceuticals Inc., USA × 3 listings | ANDA | View NDC → |
| 0.3 mg | Sublingual | Golden State Medical Supply, Inc. × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Golden State Medical Supply, Inc. × 2 listings | ANDA | View NDC → |
| 0.6 mg | Sublingual | Golden State Medical Supply, Inc. × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Henry Schein, Inc. × 3 listings | NDA | View NDC → |
| 0.4 mg | Sublingual | HF Acquisition Co LLC, DBA HealthFirst × 6 listings | ANDA | View NDC → |
| 0.3 mg | Sublingual | Lifestar Pharma LLC × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Lifestar Pharma LLC × 2 listings | ANDA | View NDC → |
| 0.6 mg | Sublingual | Lifestar Pharma LLC × 2 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | Medical Purchasing Solutions, LL | ANDA | View NDC → |
| 0.4 mg | Sublingual | Medical Purchasing Solutions, LLC × 8 listings | ANDA | View NDC → |
| 0.3 mg | Sublingual | Mylan Pharmaceuticals Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 0.4 mg | Sublingual | Mylan Pharmaceuticals Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 0.6 mg | Sublingual | Mylan Pharmaceuticals Inc. | NDA AUTHORIZED GENERIC | View NDC → |
| 0.3 mg | Sublingual | Natco Pharma USA LLC | ANDA | View NDC → |
| 0.4 mg | Sublingual | Natco Pharma USA LLC | ANDA | View NDC → |
| 0.6 mg | Sublingual | Natco Pharma USA LLC | ANDA | View NDC → |
| 0.4 mg | Sublingual | NorthStar RxLLC | ANDA | View NDC → |
| 0.4 mg | Sublingual | NuCare Pharmaceuticals, Inc. | ANDA | View NDC → |
| 0.4 mg | Sublingual | NuCare Pharmaceuticals,Inc. × 4 listings | ANDA | View NDC → |
| 0.4 mg | Sublingual | NuCare Pharmaceuticals,Inc. | NDA | Find on DailyMed ↗ |
| 0.3 mg | Sublingual | Parke-Davis Div of Pfizer Inc × 2 listings | NDA | View NDC → |
| 💊Topical cream, ointment or gel | ||||
| 20 mg/g | Topical | Encube Ethicals, Inc. | ANDA | View NDC → |
| 20 mg/g | Topical | HF Acquisition Co LLC, DBA HealthFirst × 2 listings | ANDA | View NDC → |
| 20 mg/g | Topical | Savage Laboratories a division of Fougera Pharmaceuticals, LLC | ANDA | View NDC → |
| 20 mg/g | Topical | Savage Laboratories a division of Fougera Pharmaceuticals Inc. × 2 listings | ANDA | View NDC → |
Showing 200 of 238 products — FDA National Drug Code Directory. See every product, package size and price: browse all 238 Nitroglycerin NDCs →
📈 What people report — real-world data (FDA FAERS)
After a medicine reaches the market, patients, doctors and drugmakers can send the FDA reports of problems they think may be linked to it. Here’s what’s been reported for Nitroglycerin — a signal of what to watch for, not proof the drug caused it.
Source: openFDA, from the FDA Adverse Event Reporting System (FAERS). These are voluntary reports — they don’t prove the drug caused the effect, and counts reflect how often something was reported, not how often it actually happens. Reports also often name the very problem the medicine is taken for — a common reason to file one is that the drug didn’t help — so for a pain reliever you may see “pain” high on the list; that points to why the report was filed, not to the drug causing the symptom. This counts every report that lists Nitroglycerin in any role, so the total runs higher than the FDA’s official dashboard, which counts only cases where the drug is the suspect. For the authoritative figures, see the FDA FAERS Public Dashboard. Always talk to your pharmacist or doctor.
🏛️ The road to your pharmacy
How Nitroglycerin went from FDA review to the pharmacy shelf — the key milestones in its regulatory journey.
Source: Drugs@FDA.
🚨 Recall history
A recall is when a specific batch of a medicine is pulled from the market — usually a manufacturing issue, not a problem with the drug itself. Class I is most serious, Class III least.
Source: openFDA drug enforcement (recall) reports.
RxNorm Concept Web — From Ingredient to Every Form and Strength
This page starts with one ingredient concept (IN). The branches below show its dose-form concepts (SCDF), then the available clinical drug and strength concepts (SCD). Combination products remain separate concepts with their own pages.
RxCUI 4917 12 dose forms · 33 strengths
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Dose form (SCDF) Buccal Tablet RxCUI 542230No current FDA listingClinical drug / strength (SCD) 2 MGRxCUI 5422393 MGRxCUI 5422665 MGRxCUI 542269 -
Dose form (SCDF) Extended Release Oral Capsule RxCUI 373105No current FDA listing -
Dose form (SCDF) Injectable Solution RxCUI 377109In current FDA listingsClinical drug / strength (SCD) 1 MG/MLRxCUI 245276 -
Dose form (SCDF) Injection RxCUI 1868493In current FDA listingsClinical drug / strength (SCD) 10 ML nitroglycerin 5 MG/MLRxCUI 237205250 ML nitroglycerin 0.1 MG/MLRxCUI 1868562250 ML nitroglycerin 0.2 MG/MLRxCUI 312004250 ML nitroglycerin 0.4 MG/MLRxCUI 1868494 -
Dose form (SCDF) Mucosal Spray RxCUI 705128In current FDA listingsClinical drug / strength (SCD) 0.4 MG/ACTUATRxCUI 705129 -
Dose form (SCDF) Oral Capsule RxCUI 379729In current FDA listingsClinical drug / strength (SCD) 6.5 MGRxCUI 3921739 MGRxCUI 392174 -
Dose form (SCDF) Rectal Ointment RxCUI 393438In current FDA listings -
Dose form (SCDF) Sublingual Powder RxCUI 1810782In current FDA listingsClinical drug / strength (SCD) 0.4 MGRxCUI 1799428 -
Dose form (SCDF) Sublingual Tablet RxCUI 373106In current FDA listings -
Dose form (SCDF) Sustained Release Buccal Tablet RxCUI 373104No current FDA listingClinical drug / strength (SCD) 1 MGRxCUI 3141211.5 MGRxCUI 3120102 MGRxCUI 3120163 MGRxCUI 3120175 MGRxCUI 314122 -
Dose form (SCDF) Topical Ointment RxCUI 374405In current FDA listingsClinical drug / strength (SCD) 0.02 MG/MGRxCUI 242946 -
Dose form (SCDF) Transdermal System RxCUI 1805880In current FDA listingsClinical drug / strength (SCD) 24 HR nitroglycerin 0.1 MG/HRRxCUI 86165724 HR nitroglycerin 0.2 MG/HRRxCUI 48614824 HR nitroglycerin 0.3 MG/HRRxCUI 89968824 HR nitroglycerin 0.4 MG/HRRxCUI 48615224 HR nitroglycerin 0.6 MG/HRRxCUI 48614624 HR nitroglycerin 0.8 MG/HRRxCUI 899703
Look up RxCUI 4917 in the RxCUI Atlas →
RxNorm is the U.S. National Library of Medicine’s normalized drug vocabulary. Its concept hierarchy can include forms that are not currently marketed; the status on each branch compares that concept with current FDA listings. RxCUIs identify vocabulary concepts, not individual packages or manufacturers.
📦 Supply & shortage status
Whether Nitroglycerin is in short supply in the U.S. right now, plus any shortage history the FDA has on record. A shortage usually reflects a manufacturing or demand issue — not a safety problem with the drug.
Source: openFDA, from the FDA Drug Shortages database.
🏷️ Sold under these brand names
🏭 Manufacturers & labelers
…and 16 more on the FDA NDC directory.
RxNorm drug class
Nitroglycerin belongs to the Nitrate Vasodilator class.
Classified by RxNorm RxClass — the U.S. National Library of Medicine's standardized drug-classification service (Established Pharmacologic Class from the FDA, the ATC drug family from the WHO, and mechanism of action). Reference only, not medical advice.
🔬 Where this comes from
Core label, product, RxNorm, safety, and utilization data on this page come from the sources identified below. AI-written, editorial, and licensed sections are labeled separately.
How we combine label and product data
HelloPharmacist combines public FDA and NLM records; we don’t author the underlying clinical facts. We identified 35 FDA-filed SPL label sets within the page’s selected clinical scope after exact ingredient or ingredient-combination matching and applicable route/form matching. The representative label is the starting point for the displayed reference monograph; the 12 largest stored in-scope SPL records, which may include that representative, are compared section by section, and the longest available version of each section is retained. Forms, routes, brands, labelers, product-listed strengths, and product-record counts are aggregated separately from ingredient-matched FDA NDC Directory records; package records listed above are associated with the linked SPL; and the normalized concept hierarchy comes from NLM RxNorm.
For canonical ingredient pages, bounded product-attributed indication and administration excerpts may be added to the AI evidence, and the generator is instructed to preserve available product, brand, route, and form qualifiers instead of treating one label as universal. Where a section is identified as AI-written, its plain-language text is generated from bounded label evidence. New draft drug pages remain in the admin review queue before first publication. Greenstone LLC is the representative DailyMed label linked for verification and dates; it is not the sole source used for the page.
This is general education, not medical advice — always consult your doctor or pharmacist about your medications and any medical condition. For the exact wording of the linked representative label, view that label on DailyMed; some displayed composite sections may come from other in-scope SPL labels. Learn how we use AI and our data sources & update cadence.