Eptifibatide

52 interactions 3 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abrocitinib Defibrotide Injection Sertraline Flurbiprofen Ketorolac Nasal Spray Naproxen
2 Contraindicated 43 Major 7 Moderate
All (52) Contraindicated (2) Major (43) Moderate (7)

Contraindicated

Eptifibatide Abrocitinib Cibinqo Explained Increased risk of bleeding Details Eptifibatide Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Eptifibatide Sertraline Explained An increased risk of bleeding Details Eptifibatide Apixaban Eliquis Explained Increased risk of bleeding and can cause serious, potentially fatal bleeding Details Eptifibatide Aspirin Acuprin® Increased risk of bleeding Details Eptifibatide Aspirin Rectal Aspirin Increased risk of bleeding Details Eptifibatide Betrixaban Bevyxxa® Increased risk of bleeding Details Eptifibatide Anagrelide Agrylin Increased bleeding risk Details Eptifibatide Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Eptifibatide Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Eptifibatide Clopidogrel Plavix Increased risk of bleeding Details Eptifibatide Dabigatran Pradaxa® Increased risk of bleeding Details Eptifibatide Dabigatran Etexilate Increased risk of bleeding Details Eptifibatide Dalteparin Injection Fragmin Increased risk of bleeding Details Eptifibatide Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Eptifibatide Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Eptifibatide Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Eptifibatide Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Eptifibatide Dipyridamole Permole® Increased risk of bleeding Details Eptifibatide Edoxaban Savaysa Increased risk of bleeding Details Eptifibatide Enoxaparin Lovenox Increased risk of bleeding Details Eptifibatide Enoxaparin Injection Lovenox Increased risk of bleeding Details Eptifibatide Etodolac Lodine An increased risk of bleeding Details Eptifibatide Fenoprofen Fenopron An increased risk of bleeding Details Eptifibatide Flurbiprofen Ansaid An increased risk of bleeding Details Eptifibatide Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Eptifibatide Fondaparinux Arixtra Increased risk of bleeding Details Eptifibatide Fondaparinux Injection Arixtra Increased risk of bleeding Details Eptifibatide Heparin Increased risk of bleeding Details Eptifibatide Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Eptifibatide Ibrutinib Imbruvica Increased risk of bleeding Details Eptifibatide Ibuprofen Addaprin An increased risk of bleeding Details Eptifibatide Ketoprofen Actron® An increased risk of bleeding Details Eptifibatide Ketorolac Acular An increased risk of bleeding Details Eptifibatide Ketorolac Injection Acular An increased risk of bleeding Details Eptifibatide Ketorolac Nasal Spray Sprix An increased risk of bleeding Details Eptifibatide Ketorolac Ophthalmic Acular An increased risk of bleeding Details Eptifibatide Meclofenamate Meclodium® An increased risk of bleeding Details Eptifibatide Mefenamic Acid Ponstel® An increased risk of bleeding Details Eptifibatide Meloxicam Alloxate An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.