Darifenacin

Major

Darifenacin Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of paralytic ileus Details Darifenacin Sertraline Explained Increased CYP2D6 substrate exposure Details Darifenacin Buprenorphine Belbuca Explained An increased risk of paralytic ileus Details Darifenacin Asenapine Transdermal Patch Secuado Increased exposure of CYP2D6 substrate and inhibitor and an increased asenapine exposure Details Darifenacin Encorafenib Braftovi Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Darifenacin Fentanyl Transdermal Patch Duragesic® Increased risk of urinary retention and/or severe constipation, which may lead to paralytic ileus Details Darifenacin Flecainide Tambocor® Increased flecainide exposure with an increased risk of cardiac arrhythmias Details Darifenacin Glucagon Injection Baqsimi Increased risk of gastrointestinal side effects Details Darifenacin Glucagon Injection / Solution Baqsimi Increased risk of gastrointestinal side effects Details Darifenacin Glucagon Nasal Powder Baqsimi Increased risk of gastrointestinal side effects Details Darifenacin Glycopyrronium Topical Cuvposa® An increased risk of anticholinergic side effects Details Darifenacin Hydromorphone Injection Dilaudid Increased risk of urinary retention and/or severe constipation leading to paralytic ileus Details Darifenacin Hydromorphone Rectal available generically Increased risk of urinary retention and/or severe constipation leading to paralytic ileus Details Darifenacin Hydroxychloroquine Plaquenil An increased risk of seizures Details Darifenacin Ketoconazole Topical Extina® Foam Increased darifenacin exposure and increased darifenacin-related adverse reactions Details Darifenacin Lefamulin Xenleta Increased sensitive CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related toxicities associated wi... Details Darifenacin Lenacapavir Injection Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Darifenacin Lenacapavir Oral Sunlenca Increased sensitive CYP3A substrate exposure and an increased risk of sensitive CYP3A substrate-mediated adverse reactions Details Darifenacin Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Darifenacin Mitapivat Aqvesme Reduced CYP3A substrate exposure Details Darifenacin Morphine Injection Astramorph® PF Increased risk of urinary retention, severe constipation, and paralytic ileus Details Darifenacin Olutasidenib Rezlidhia Reduced sensitive CYP3A substrate exposure Details

Moderate

Darifenacin Trospium / Xanomeline Cobenfy Explained An increased risk of anticholinergic adverse reactions (eg, dry mouth, constipation), an increased darifenacin exposure and an inc... Details