Capivasertib

17 interactions 2 explained in plain English
Also sold as: Truqap
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Methylergonovine Ketoconazole Topical Letermovir Injection Loperamide Finerenone Nafcillin Injection
14 Major 3 Moderate
All (17) Major (14) Moderate (3)

Major

Capivasertib Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine exposure and reduced active metabolite (morphine) exposure Details Capivasertib Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine-related toxicity Details Capivasertib Bedaquiline Sirturo Increased bedaquiline exposure Details Capivasertib Brexpiprazole Rexulti Increased brexpiprazole exposure Details Capivasertib Cyclosporine Injection Atopica Increased capivasertib exposure and an increased risk of capivasertib-related adverse reactions Details Capivasertib Cyclosporine Ophthalmic Cequa Increased capivasertib exposure and an increased risk of capivasertib-related adverse reactions Details Capivasertib Doxorubicin Adriamycin Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Capivasertib Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Capivasertib Ketoconazole Topical Extina® Foam Increased capivasertib exposure and an increased risk of capivasertib-related adverse reactions Details Capivasertib Letermovir Injection Prevymis Increased capivasertib exposure and an increased risk of capivasertib-related adverse reactions Details Capivasertib Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Capivasertib Methylergonovine Methergine Increased methylergonovine exposure Details Capivasertib Nafcillin Injection Unipen® Injection Reduced capivasertib exposure and reduced efficacy of capivasertib Details Capivasertib Nifedipine Adalat® Increased NIFEdipine exposure Details

Moderate

Capivasertib Dofetilide Tikosyn Increased dofetilide exposure Details Capivasertib Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Capivasertib Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details

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