Fam-Trastuzumab Deruxtecan-Nxki Injection

15 interactions 39 cited references
Also sold as: Enhertu Enhertu®
About Fam-Trastuzumab Deruxtecan-Nxki Injection

Fam-trastuzumab deruxtecan-nxki injection is used to treat a certain type of breast cancer that cannot be removed by surgery, that has spread to other parts of the body, or has come back after another breast cancer treatment. It is also used to treat certain types of gastric cancer (cancer of the stomach) in adults tha… Read the full Fam-Trastuzumab Deruxtecan-Nxki Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 6 Major
All (15) Contraindicated (9) Major (6)

Contraindicated

Fam-Trastuzumab Deruxtecan-Nxki Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Fam-Trastuzumab Deruxtecan-Nxki Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Fam-Trastuzumab Deruxtecan-Nxki Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.