Candesartan

51 interactions 1 explained in plain English 165 cited references
Also sold as: Atacand Atacand®
About Candesartan

Candesartan is an angiotensin II receptor antagonist used to treat high blood pressure and congestive heart failure. Read the full Candesartan drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Candesartan Lisinopril Prinivil Explained Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Benazepril Lotensin Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Lithium Increased risk of lithium toxicity Details Candesartan Trimethoprim Primsol Increased risk of hyperkalemia Details Candesartan Captopril Capoten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Carboplatin Kyxata Increased risk of severe neutropenia Details Candesartan Carboplatin Injection Kyxata Increased risk of severe neutropenia Details Candesartan Cyclosporine Injection Atopica An increased risk of hyperkalemia Details Candesartan Cyclosporine Ophthalmic Cequa An increased risk of hyperkalemia Details Candesartan Digoxin Cardoxin® An increased digoxin exposure Details Candesartan Enalapril Epaned Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Fosinopril Monopril® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Furosemide Injection Disal Severe hypotension and deterioration in renal function, including renal failure Details Candesartan Moexipril Univasc® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Candesartan Perindopril Aceon Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details

Moderate

Candesartan Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Candesartan Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Insulin Afrezza Increased risk of hypoglycemia Details Candesartan Insulin Aspart, Recombinant Fiasp Increased risk of hypoglycemia Details Candesartan Insulin Bovine Increased risk of hypoglycemia Details Candesartan Insulin Degludec Tresiba Increased risk of hypoglycemia Details Candesartan Insulin Detemir Levemir Increased risk of hypoglycemia Details Candesartan Insulin Glargine, Recombinant Basaglar Increased risk of hypoglycemia Details Candesartan Insulin Glulisine Apidra Increased risk of hypoglycemia Details Candesartan Insulin Lispro, Recombinant Admelog Increased risk of hypoglycemia Details Candesartan Ma Huang Reduced effectiveness of angiotensin II receptor antagonists Details Candesartan Yohimbine Reduced angiotensin II receptor antagonist effectiveness Details Candesartan Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Diclofenac Transdermal Patch Flector Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Etodolac Lodine Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Fenoprofen Fenopron Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Flurbiprofen Ansaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Flurbiprofen Ophthalmic Ocufen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Ibuprofen Addaprin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Candesartan Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Increased risk of hypoglycemia Details Candesartan Insulin Detemir (Rdna Origin) Injection Levemir Increased risk of hypoglycemia Details Candesartan Insulin Glulisine (Rdna Origin) Injection Apidra Increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.