Evening Primrose

23 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

23 Moderate
All (23) Moderate (23)

Moderate

Evening Primrose Aspirin Acuprin® Increased risk of bleeding Details Evening Primrose Aspirin Rectal Aspirin Increased risk of bleeding Details Evening Primrose Anagrelide Agrylin Increased risk of bleeding Details Evening Primrose Becaplermin Topical Regranex Increased risk of bleeding Details Evening Primrose Clopidogrel Plavix Increased risk of bleeding Details Evening Primrose Dalteparin Injection Fragmin Increased risk of bleeding Details Evening Primrose Defibrotide Injection Defitelio Increased risk of bleeding Details Evening Primrose Diazepam Nasal Spray Valtoco Reduced anticonvulsant effectiveness Details Evening Primrose Diazepam Rectal Diastat Reduced anticonvulsant effectiveness Details Evening Primrose Dipyridamole Permole® Increased risk of bleeding Details Evening Primrose Enoxaparin Lovenox Increased risk of bleeding Details Evening Primrose Enoxaparin Injection Lovenox Increased risk of bleeding Details Evening Primrose Epoprostenol Flolan Increased risk of bleeding Details Evening Primrose Ethosuximide Zarontin Reduced anticonvulsant effectiveness Details Evening Primrose Felbamate Felbatol Reduced anticonvulsant effectiveness Details Evening Primrose Fondaparinux Arixtra Increased risk of bleeding Details Evening Primrose Fondaparinux Injection Arixtra Increased risk of bleeding Details Evening Primrose Heparin Increased risk of bleeding Details Evening Primrose Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Evening Primrose Iloprost Aurlumyn Increased risk of bleeding Details Evening Primrose Levetiracetam Elepsia Reduced anticonvulsant effectiveness Details Evening Primrose Levetiracetam Injection Elepsia Reduced anticonvulsant effectiveness Details Evening Primrose Methsuximide Celontin Reduced anticonvulsant effectiveness Details

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