Pancrelipase

Name: Pancrelipase Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

3 interactions 76 cited references

Also sold as: Creon® Pancreaze® Pertzye® Ultresa® Viokace® Zenpep®

About Pancrelipase

Pancrelipase delayed-release capsules (Creon, Pancreaze, Pertzye, Ultresa, Zenpep) are used to improve digestion of food in children and adults who do not have enough pancreatic enzymes (substances needed to break down food so it can be digested) because they have a condition that affects the pancreas (a gland that pro… Read the full Pancrelipase drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

2 Moderate 1 Minor

All (3) Moderate (2) Minor (1)

Moderate

Pancrelipase Acarbose Prandase® Reduced effectiveness of acarbose Details Pancrelipase Miglitol Glyset® Reduced effectiveness of miglitol Details

Minor

Pancrelipase L-Methylfolate Decreased l-methylfolate serum levels Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.