Digoxin
453 interactions 2 explained in plain English 980 cited referencesDigoxin is a cardiac glycoside used to treat heart failure and abnormal heart rhythms by strengthening the heart's contractions and slowing heart rate. Read the full Digoxin drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Digoxin Omeprazole Gastrobim Increased digoxin exposure, an increased risk of digoxin toxicity (nausea, vomiting, arrhythmias) and an increased risk of hypomag... Details Digoxin Albuterol Oral Inhalation Accuneb® Explained Reduced digoxin exposure Details Digoxin Lisinopril Prinivil An increased digoxin exposure Details Digoxin Colchicine Colcrys An increased risk of myopathy, including rhabdomyolysis Details Digoxin Simvastatin Flolipid Increased digoxin exposure and an increased risk of digoxin-related adverse effects Details Digoxin Abrocitinib Cibinqo Increased exposure of P-glycoprotein substrate Details Digoxin Acarbose Prandase® Reduced digoxin exposure Details Digoxin Acetazolamide Diamox® Sequels® Digitalis toxicity (nausea, vomiting, arrhythmias) Details Digoxin Asciminib Scemblix Increased digoxin exposure and an increased risk of digoxin-related adverse effects Details Digoxin Aspirin Acuprin® Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Aspirin Rectal Aspirin Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Azithromycin AzaSite An increased digoxin exposure Details Digoxin Belumosudil Rezurock Increased P-gp substrate exposure Details Digoxin Benazepril Lotensin An increased digoxin exposure Details Digoxin Atorvastatin Atorvaliq Increased digoxin exposure Details Digoxin Alogliptin Nesina Increased digoxin exposure Details Digoxin Amlodipine Amvaz® An increased risk of bradycardia and an increased risk of complete heart block Details Digoxin Azilsartan Edarbi An increased digoxin exposure Details Digoxin Brigatinib Alunbrig Increased digoxin exposure Details Digoxin Bromfenac Ophthalmic Bromday® Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Canagliflozin Invokana Increased digoxin exposure Details Digoxin Capmatinib Tabrecta Increased P-gp substrate exposure and an increased risk of increased adverse reactions Details Digoxin Captopril Capoten® Increased digoxin exposure Details Digoxin Cholestyramine Resin Locholest® Reduced digoxin exposure Details Digoxin Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Digoxin Colestipol Colestid Reduced digoxin exposure Details Digoxin Cyclosporine Injection Atopica Increased digoxin exposure and an increased risk of digoxin toxicity Details Digoxin Cyclosporine Ophthalmic Cequa Increased digoxin exposure and an increased risk of digoxin toxicity Details Digoxin Demeclocycline Declomycin® Increased digoxin levels and digoxin toxicity (nausea, vomiting, cardiac arrhythmias) Details Digoxin Aceclofenac Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Acemetacin Increased digoxin exposure and prolonged half-life of digoxin Details Digoxin Activated Charcoal Reduced digoxin exposure Details Digoxin Adagrasib Krazati Increased exposure to P-gp substrates and an increased risk of P-gp substrates-related adverse effects Details Digoxin Albuterol ProAir Reduced digoxin exposure Details Digoxin Alprazolam Xanax Increased digoxin exposure Details Digoxin Aluminum Carbonate, Basic Reduced digoxin exposure Details Digoxin Aluminum Hydroxide AlternaGEL® Reduced digoxin exposure Details Digoxin Aluminum Phosphate Reduced digoxin exposure Details Digoxin Amiodarone Nexterone Increased digoxin exposure and an increased efficacy of amiodarone DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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