Brigatinib
136 interactions 323 cited referencesBrigatinib is used to treat a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the bodys. Brigatinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread… Read the full Brigatinib drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Brigatinib Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Brigatinib Levoketoconazole Recorlev Increased CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related adverse reaction Details Brigatinib Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Mifepristone Korlym Increased CYP3A4 substrate with NTI exposure Details Brigatinib Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Ranolazine Aspruzyo Altered ranolazine exposure and an increased CYP3A4 substrate exposure Details Brigatinib Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Brigatinib Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Brigatinib Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Brigatinib Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine DetailsMajor
Brigatinib Abametapir Increased exposure of CYP3A4 substrate Details Brigatinib Relugolix Orgovyx Increased relugolix exposure Details Brigatinib Asciminib Scemblix Increased CYP3A4 exposure and an increased risk of CYP3A4-related adverse reactions Details Brigatinib Atogepant Qulipta Reduced atogepant exposure Details Brigatinib Cariprazine Vraylar Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Brigatinib Amlodipine Amvaz® Reduced amLODIPine exposure Details Brigatinib Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Brigatinib Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Brigatinib Alfentanil Reduced ALfentanil exposure, reduced efficacy of ALfentanil and an increased risk of a withdrawal syndrome Details Brigatinib Apalutamide Erleada Reduced brigatinib efficacy Details Brigatinib Aprepitant Aponvie Increased brigatinib exposure Details Brigatinib Artemether Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine, loss of antimalarial efficacy, reduced CYP3... Details Brigatinib Atazanavir Reyataz Increased brigatinib exposure Details Brigatinib Avacopan Tavneos Increased exposure to CYP3A4 substrate Details Brigatinib Belzutifan Welireg Reduced CYP3A4 substrates with NTI exposure and reduced efficacy of CYP3A4 substrates with NTI Details Brigatinib Berotralstat Orladeyo Increased CYP3A4 substrate exposure and an increased CYP3A4 substrate-related adverse reactions Details Brigatinib Boceprevir Increased brigatinib exposure Details Brigatinib Bosentan Decreased brigatinib exposure and efficacy Details Brigatinib Carbamazepine Carbatrol Reduced brigatinib efficacy Details Brigatinib Ceritinib Zykadia Increased exposure of CYP3A substrate Details Brigatinib Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Brigatinib Ciprofloxacin Increased brigatinib exposure Details Brigatinib Clarithromycin Biaxin Increased brigatinib exposure Details Brigatinib Cobicistat Tybost Increased brigatinib exposure Details Brigatinib Conivaptan Vaprisol Increased brigatinib exposure Details Brigatinib Crizotinib Xalkori Increased brigatinib exposure Details Brigatinib Cyclosporine Atopica Increased brigatinib exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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