Moxifloxacin

322 interactions 387 cited references

Also sold as: Avelox Avelox® Vigamox

About Moxifloxacin

Moxifloxacin is a fluoroquinolone antibiotic used to treat bacterial infections including pneumonia, skin, and abdominal infections. Read the full Moxifloxacin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Saquinavir Terfenadine Thioridazine Pimozide Sparfloxacin Piperaquine

12 Contraindicated 290 Major 20 Moderate

All (322) Contraindicated (12) Major (290) Moderate (20)

Contraindicated

Moxifloxacin Bepridil An increased risk of QT interval prolongation Details Moxifloxacin Cisapride Propulsid® Increased risk of QT interval prolongation Details Moxifloxacin Dronedarone Multaq Increased risk of QT interval prolongation Details Moxifloxacin Levoketoconazole Recorlev An increased risk of QT interval prolongation, an increased risk of serious hepatotoxicity and drug-induced liver injury Details Moxifloxacin Mesoridazine An increased risk of QT interval prolongation Details Moxifloxacin Pimozide An increased risk of QT interval prolongation Details Moxifloxacin Piperaquine An increased risk of QT interval prolongation Details Moxifloxacin Saquinavir An increased risk of QT interval prolongation Details Moxifloxacin Sparfloxacin An increased risk of QT interval prolongation Details Moxifloxacin Terfenadine An increased risk of QT interval prolongation Details Moxifloxacin Thioridazine An increased risk of QT interval prolongation Details Moxifloxacin Ziprasidone Geodon An increased risk of QT interval prolongation Details

Major

Moxifloxacin Amitriptyline Elavil Increased risk of QT interval prolongation Details Moxifloxacin Sertraline An increased risk of QT interval prolongation Details Moxifloxacin Buprenorphine Belbuca An increased risk of QT interval prolongation Details Moxifloxacin Relugolix Orgovyx Increased risk of QT interval prolongation Details Moxifloxacin Acarbose Prandase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Moxifloxacin Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Moxifloxacin Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Moxifloxacin Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Moxifloxacin Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Moxifloxacin Azathioprine Azasan An increased risk of hepatotoxicity Details Moxifloxacin Azithromycin AzaSite Increased risk of QT interval prolongation Details Moxifloxacin Alfuzosin UroXatral Increased risk of QT interval prolongation Details Moxifloxacin Alogliptin Nesina Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Anagrelide Agrylin Increased anagrelide exposure and increased risk of QT interval prolongation Details Moxifloxacin Bedaquiline Sirturo Increased risk of QT interval prolongation Details Moxifloxacin Budesonide Entocort An increased risk of tendon rupture Details Moxifloxacin Budesonide Nasal Spray Rhinocort An increased risk of tendon rupture Details Moxifloxacin Budesonide Oral Inhalation Pulmicort An increased risk of tendon rupture Details Moxifloxacin Canagliflozin Invokana Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Chloroquine Aralen® Increased risk of QT interval prolongation Details Moxifloxacin Dapagliflozin Farxiga Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Moxifloxacin Dasatinib Phyrago Increased risk of QT interval prolongation Details Moxifloxacin Deflazacort Emflaza An increased risk of tendon rupture Details Moxifloxacin Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Moxifloxacin Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Moxifloxacin Dexamethasone Injection Decadron An increased risk of tendon rupture Details Moxifloxacin Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) An increased risk of tendon rupture Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.