Amiodarone
141 interactions 9 explained in plain English
Also sold as:
Nexterone
Pacerone
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Ketoconazole Topical
Deuruxolitinib
Colchicine
Glasdegib
Galantamine
Miconazole Vaginal
Contraindicated
Amiodarone Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of fatal toxicity Details Amiodarone Deuruxolitinib Increased deuruxolitinib exposure and an increased risk of deuruxolitinib-related adverse effects such as thrombosis Details Amiodarone Ketoconazole Topical Extina® Foam Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation DetailsMajor
Amiodarone Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Amiodarone Abametapir Explained Increased exposure of CYP3A4 substrate Details Amiodarone Amitriptyline Elavil Explained An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Sertraline Explained An increased risk of QT interval prolongation Details Amiodarone Buprenorphine Belbuca Explained An increased risk of QT interval prolongation, increased buprenorphine exposure and an increased risk of buprenorphine-related adv... Details Amiodarone Relugolix Orgovyx Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Amiodarone Simvastatin Flolipid Explained Increased exposure to simvastatin and an increased risk of myopathy or rhabdomyolysis Details Amiodarone Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Amiodarone Arsenic Trioxide Trisenox Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Amiodarone Aripiprazole Injection Abilify An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Arsenic Trioxide Injection Trisenox Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Amiodarone Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Amiodarone Azathioprine Azasan An increased risk of hepatotoxicity Details Amiodarone Azithromycin AzaSite An increased risk of cardiotoxicity (QT interval prolongation, torsades de pointes, cardiac arrest) Details Amiodarone Betrixaban Bevyxxa® Increased betrixaban exposure and increased risk of bleeding Details Amiodarone Abiraterone Abirtega Increased amiodarone exposure and an increased risk of amiodarone-related adverse effects Details Amiodarone Afatinib Gilotrif Increased exposure of afatinib Details Amiodarone Alfuzosin UroXatral An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Anagrelide Agrylin An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Bedaquiline Sirturo Increased bedaquiline exposure and an increased risk of QT interval prolongation Details Amiodarone Bendamustine Injection Belrapzo Increased bendamustine exposure and an increased risk of bendamustine-related adverse effects Details Amiodarone Budesonide Entocort Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Amiodarone Budesonide Nasal Spray Rhinocort Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Amiodarone Budesonide Oral Inhalation Pulmicort Increased budesonide exposure and an increased risk of budesonide-related adverse effects Details Amiodarone Chloroquine Aralen® An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Clopidogrel Plavix Increased amiodarone exposure Details Amiodarone Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Amiodarone Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Amiodarone Dasatinib Phyrago An increased risk of QT interval prolongation and torsade de pointes Details Amiodarone Deferasirox Exjade Altered exposure of amiodarone Details Amiodarone Degarelix Injection Firmagon Increased risk of QT prolongation Details Amiodarone Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Amiodarone Dexamethasone Injection Decadron Reduced amiodarone exposure and reduced efficacy of amiodarone Details Amiodarone Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced amiodarone exposure and reduced efficacy of amiodarone Details Amiodarone Digoxin Cardoxin® Increased digoxin exposure and an increased efficacy of amiodarone Details Amiodarone Disopyramide Norpace Increased antiarrhythmic levels, QTc prolongation Details Amiodarone Docetaxel Beizray Increase in docetaxel exposure and risk of toxicity DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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