Amiodarone

Name: Amiodarone Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

141 interactions 9 explained in plain English

Also sold as: Nexterone Pacerone

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketoconazole Topical Deuruxolitinib Colchicine Glasdegib Galantamine Miconazole Vaginal

3 Contraindicated 111 Major 26 Moderate 1 Minor

All (141) Contraindicated (3) Major (111) Moderate (26) Minor (1)

Contraindicated

Amiodarone Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of fatal toxicity Details Amiodarone Deuruxolitinib Increased deuruxolitinib exposure and an increased risk of deuruxolitinib-related adverse effects such as thrombosis Details Amiodarone Ketoconazole Topical Extina® Foam Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.