Metergoline

Name: Metergoline Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

7 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dihydroergotamine Injection Dihydroergotamine Nasal Spray Ketoconazole Topical Clotrimazole Clotrimazole Lozenge Clotrimazole Topical

3 Contraindicated 4 Major

All (7) Contraindicated (3) Major (4)

Contraindicated

Metergoline Dihydroergotamine Injection DHE-45® Injection An increased risk of ergotism Details Metergoline Dihydroergotamine Nasal Spray Migranal An increased risk of ergotism Details Metergoline Ketoconazole Topical Extina® Foam Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details

Major

Metergoline Clotrimazole Aardora Anti-Fungal Maximum Strength Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Metergoline Clotrimazole Lozenge Mycelex® Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Metergoline Clotrimazole Topical Cruex Antifungal Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Metergoline Clotrimazole Vaginal Gyne-Lotrimin 3® Cream Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.