Goldenseal
10 interactions
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Aug 8, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Goldenseal Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Goldenseal Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Goldenseal Methylergonovine Methergine Increased methylergonovine exposure Details Goldenseal Nifedipine Adalat® Increased NIFEdipine exposure DetailsModerate
Goldenseal Dofetilide Tikosyn Increased dofetilide exposure Details Goldenseal Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Goldenseal Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Goldenseal Metformin Fortamet® Decreased metformin exposure Details Goldenseal Midazolam Nasal Spray Nayzilam Increased plasma concentrations of midazolam Details Goldenseal Midazolam Injection Nayzilam Increased plasma concentrations of midazolam DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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