Benznidazole

Name: Benznidazole Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

9 interactions 28 cited references

About Benznidazole

Benznidazole is used to treat Chagas disease (caused by a parasite) in children 2 to 12 years old. Benznidazole is in a class of medications called antiprotozoals. It works by killing the organism that can cause Chagas disease. Read the full Benznidazole drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Capecitabine Cholera Vaccine, Live Doxifluridine Fluorouracil Tegafur Fluorouracil Injection

7 Major 2 Moderate

All (9) Major (7) Moderate (2)

Major

Benznidazole Capecitabine Xeloda Increased exposure of 5-fluorouracil Details Benznidazole Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Benznidazole Doxifluridine Increased exposure of 5-fluorouracil Details Benznidazole Fluorouracil Adrucil Increased exposure of 5-fluorouracil Details Benznidazole Tegafur Increased exposure of 5-fluorouracil Details Benznidazole Fluorouracil Injection Adrucil Increased exposure of 5-fluorouracil Details Benznidazole Fluorouracil Topical Carac Increased exposure of 5-fluorouracil Details

Moderate

Benznidazole Lixisenatide Delayed therapeutic effect Details Benznidazole Lixisenatide Injection Adlyxin® Delayed therapeutic effect Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.