Gepirone

77 interactions 5 explained in plain English
Also sold as: Exxua
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Gepirone Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of serotonin syndrome Details Gepirone Amitriptyline Elavil Explained Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Sertraline Explained Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Buprenorphine Belbuca Explained Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Amisulpride Injection Barhemsys An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Arsenic Trioxide Trisenox An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Aripiprazole Injection Abilify An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Azithromycin AzaSite An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Alfuzosin UroXatral An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Anagrelide Agrylin An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Bedaquiline Sirturo An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Butorphanol Injection Butorphic An increased risk of serotonin syndrome Details Gepirone Butorphanol Nasal Spray Stadol® NS An increased risk of serotonin syndrome Details Gepirone Chloroquine Aralen® An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Cyclosporine Injection Atopica Increased gepirone exposure and an increased risk of gepirone-related adverse effects Details Gepirone Cyclosporine Ophthalmic Cequa Increased gepirone exposure and an increased risk of gepirone-related adverse effects Details Gepirone Dasatinib Phyrago An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Degarelix Injection Firmagon An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Deutetrabenazine Austedo An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Disopyramide Norpace An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Dofetilide Tikosyn An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Dolasetron Anzemet Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Dolasetron Injection Anzemet Increased risk of serotonin syndrome and an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Encorafenib Braftovi Reduced gepirone exposure; reduced efficacy of gepirone, an increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Entrectinib Rozlytrek An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Eribulin Injection Halaven An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Famotidine Calmicid An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Famotidine Injection Calmicid An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Felbamate Felbatol An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Fentanyl Transdermal Patch Duragesic® An increased risk of serotonin syndrome Details Gepirone Flecainide Tambocor® An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Foscarnet Injection Foscavir An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Galantamine Razadyne An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Gemifloxacin Factive An increased risk of QT interval prolongation and cardiac arrhythmias Details Gepirone Glasdegib Daurismo An increased risk of QT interval prolongation and cardiac arrhythmias Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.