Meropenem

31 interactions 216 cited references

Read the full Meropenem drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Estradiol Estradiol Topical Valproic Acid Levonorgestrel Levonorgestrel Intrauterine System Medroxyprogesterone

29 Major 2 Moderate

All (31) Major (29) Moderate (2)

Major

Meropenem Estradiol Delestrogen Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Estradiol Topical Divigel Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Estradiol Transdermal Patch Alora® Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Levonorgestrel After banger Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Levonorgestrel Intrauterine System Kyleena Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Medroxyprogesterone Amen® Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Bupropion Aplenzin Increased risk of seizures Details Meropenem Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Meropenem Clomipramine Anafranil Increased risk of seizures Details Meropenem Desogestrel Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Dienogest Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Drospirenone Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Estetrol Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Ethinyl Estradiol Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Ethynodiol Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Etonogestrel Nexplanon Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Gestodene Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Mestranol Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Nitisinone Increased OAT1 or OAT3 substrate exposure and an increased risk of OAT1 or OAT3 substrate-related adverse effects Details Meropenem Nomegestrol Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Norelgestromin Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Norethindrone Aygestin Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Norgestimate Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Norgestrel Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Segesterone Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Tramadol ConZip An increased risk of seizure Details Meropenem Ulipristal Ella Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Meropenem Valproic Acid Depakene® Reduced valproic acid exposure and an increased risk of seizures and status epilepticus Details

Moderate

Meropenem Probenecid Increased meropenem exposure Details Meropenem Typhoid Vaccine, Live Vivotif A decreased immunological response to the typhoid vaccine Details

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