Tedizolid Phosphate

25 interactions 5 explained in plain English
Also sold as: Sivextro
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Tedizolid Phosphate Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of serotonin syndrome Details Tedizolid Phosphate Amitriptyline Elavil Explained An increased risk of serotonin syndrome Details Tedizolid Phosphate Sertraline Explained An increased risk of serotonin syndrome Details Tedizolid Phosphate Buprenorphine Belbuca Explained An increased risk of serotonin syndrome Details Tedizolid Phosphate Simvastatin Flolipid Explained Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Alpelisib Piqray Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Butorphanol Injection Butorphic An increased risk of serotonin syndrome Details Tedizolid Phosphate Butorphanol Nasal Spray Stadol® NS An increased risk of serotonin syndrome Details Tedizolid Phosphate Dolasetron Anzemet An increased risk of serotonin syndrome Details Tedizolid Phosphate Dolasetron Injection Anzemet An increased risk of serotonin syndrome Details Tedizolid Phosphate Fentanyl Transdermal Patch Duragesic® An increased risk of serotonin syndrome Details Tedizolid Phosphate Granisetron Transdermal Patch Sancuso An increased risk of serotonin syndrome Details Tedizolid Phosphate Granisetron Injection Granisol An increased risk of serotonin syndrome Details Tedizolid Phosphate Hydromorphone Injection Dilaudid An increased risk of serotonin syndrome Details Tedizolid Phosphate Hydromorphone Rectal available generically An increased risk of serotonin syndrome Details Tedizolid Phosphate Irinotecan Camptosar Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Irinotecan Injection Camptosar Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Linezolid Injection Zyvox An increased risk of serotonin syndrome Details Tedizolid Phosphate Lithium Carbonate Lithobid An increased risk of serotonin syndrome Details Tedizolid Phosphate Methotrexate Jylamvo Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Methotrexate Injection Abitrexate® Increased BCRP substrates exposure and an increased risk of BCRP substrates-related adverse reactions Details Tedizolid Phosphate Morphine Injection Astramorph® PF An increased risk of serotonin syndrome Details Tedizolid Phosphate Nalbuphine Injection Nubain® An increased risk of serotonin syndrome Details Tedizolid Phosphate Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.