Nicotine Nasal Spray

Name: Nicotine Nasal Spray Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

5 interactions 124 cited references

Also sold as: Nicotrol Nicotrol® NS

About Nicotine Nasal Spray

Nicotine nasal spray is used to help people stop smoking. Nicotine nasal spray should be used together with a smoking cessation program, which may include support groups, counseling, or specific behavior change techniques. Nicotine nasal spray is in a class of medications called smoking cessation aids. It works by prov… Read the full Nicotine Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Tegafur

1 Major 1 Moderate 3 Minor

All (5) Major (1) Moderate (1) Minor (3)

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.