Ticlopidine

61 interactions 4 explained in plain English
Also sold as: Ticlid®
About Ticlopidine

Ticlopidine is used to reduce the risk of stroke in people who have had a stroke or have had warning signs of a stroke and who cannot be treated with aspirin. Ticlopidine is also used along with aspirin to prevent blood clots from forming in coronary stents (metal tubes surgically placed in clogged blood vessels to imp… Read the full Ticlopidine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abrocitinib Defibrotide Injection Melphalan Injection Apixaban Lumateperone Fondaparinux
2 Contraindicated 50 Major 9 Moderate
All (61) Contraindicated (2) Major (50) Moderate (9)

Contraindicated

Ticlopidine Abrocitinib Cibinqo Explained Increased risk of bleeding, and increased abrocitinib and active metabolite exposure Details Ticlopidine Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Ticlopidine Sertraline Explained An increased risk of bleeding Details Ticlopidine Apixaban Eliquis Explained Increased risk of bleeding and can cause serious, potentially fatal bleeding Details Ticlopidine Aspirin Acuprin® An increased risk of bleeding Details Ticlopidine Aspirin Rectal Aspirin An increased risk of bleeding Details Ticlopidine Atogepant Qulipta Reduced atogepant exposure Details Ticlopidine Betrixaban Bevyxxa® Increased risk of bleeding Details Ticlopidine Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Ticlopidine Amlodipine Amvaz® Reduced amLODIPine exposure Details Ticlopidine Anagrelide Agrylin Increased bleeding risk Details Ticlopidine Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Ticlopidine Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Ticlopidine Clopidogrel Plavix Reduced clopidogrel active metabolite exposure, reduced platelet inhibition and an increased risk of bleeding Details Ticlopidine Cyclosporine Injection Atopica Reduced cycloSPORINE exposure and reduced efficacy of cycloSPORINE Details Ticlopidine Cyclosporine Ophthalmic Cequa Reduced cycloSPORINE exposure and reduced efficacy of cycloSPORINE Details Ticlopidine Dabigatran Pradaxa® Increased risk of bleeding Details Ticlopidine Dabigatran Etexilate Increased risk of bleeding Details Ticlopidine Dalteparin Injection Fragmin Increased risk of bleeding Details Ticlopidine Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Ticlopidine Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Ticlopidine Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Ticlopidine Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Ticlopidine Dipyridamole Permole® An increased risk of bleeding Details Ticlopidine Edoxaban Savaysa Increased risk of bleeding Details Ticlopidine Enoxaparin Lovenox Increased risk of bleeding Details Ticlopidine Enoxaparin Injection Lovenox Increased risk of bleeding Details Ticlopidine Etodolac Lodine An increased risk of bleeding Details Ticlopidine Fenoprofen Fenopron An increased risk of bleeding Details Ticlopidine Flurbiprofen Ansaid An increased risk of bleeding Details Ticlopidine Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Ticlopidine Fondaparinux Arixtra Increased risk of bleeding Details Ticlopidine Fondaparinux Injection Arixtra Increased risk of bleeding Details Ticlopidine Heparin Increased risk of bleeding Details Ticlopidine Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Ticlopidine Ibrutinib Imbruvica Increased risk of bleeding Details Ticlopidine Ibuprofen Addaprin An increased risk of bleeding Details Ticlopidine Ketoprofen Actron® An increased risk of bleeding Details Ticlopidine Ketorolac Acular An increased risk of bleeding Details Ticlopidine Ketorolac Injection Acular An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.