Desoximetasone

32 interactions 136 cited references
Also sold as: Topicort

Read the full Desoximetasone drug information page

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Desoximetasone Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Desoximetasone Aspirin Rectal Aspirin An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Desoximetasone Bemiparin Increased risk of bleeding Details Desoximetasone Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Desoximetasone Cosyntropin False elevations of plasma cortisol levels Details Desoximetasone Ethinyl Estradiol Increased corticosteroid exposure Details Desoximetasone Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Desoximetasone Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Desoximetasone Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Desoximetasone Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Desoximetasone Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Desoximetasone Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Desoximetasone Nadroparin Increased risk of bleeding Details Desoximetasone Phenytoin Dilantin Reduced corticosteroid exposure Details Desoximetasone Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Desoximetasone Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Desoximetasone Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Desoximetasone Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Desoximetasone Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.