Prasugrel

49 interactions 3 explained in plain English
Also sold as: Effient Effient®
About Prasugrel

Prasugrel is an anti-platelet medication used to prevent heart attacks and strokes in people who've had a heart attack or severe chest pain treated with angioplasty. Read the full Prasugrel drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abrocitinib Defibrotide Injection Morphine Injection Etodolac Bromfenac Ophthalmic Edoxaban
2 Contraindicated 44 Major 3 Moderate
All (49) Contraindicated (2) Major (44) Moderate (3)

Contraindicated

Prasugrel Abrocitinib Cibinqo Explained Increased risk of bleeding Details Prasugrel Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Prasugrel Sertraline Explained An increased risk of bleeding Details Prasugrel Apixaban Eliquis Explained Increased risk of bleeding and can cause serious, potentially fatal bleeding Details Prasugrel Aspirin Acuprin® An increased risk of bleeding Details Prasugrel Aspirin Rectal Aspirin An increased risk of bleeding Details Prasugrel Betrixaban Bevyxxa® Increased risk of bleeding Details Prasugrel Anagrelide Agrylin Increased bleeding risk Details Prasugrel Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Prasugrel Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Prasugrel Clopidogrel Plavix An increased risk of bleeding Details Prasugrel Dabigatran Pradaxa® Increased risk of bleeding Details Prasugrel Dabigatran Etexilate Increased risk of bleeding Details Prasugrel Dalteparin Injection Fragmin Increased risk of bleeding Details Prasugrel Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Prasugrel Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Prasugrel Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Prasugrel Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Prasugrel Dipyridamole Permole® An increased risk of bleeding Details Prasugrel Edoxaban Savaysa Increased risk of bleeding Details Prasugrel Enoxaparin Lovenox Increased risk of bleeding Details Prasugrel Enoxaparin Injection Lovenox Increased risk of bleeding Details Prasugrel Etodolac Lodine An increased risk of bleeding Details Prasugrel Fenoprofen Fenopron An increased risk of bleeding Details Prasugrel Flurbiprofen Ansaid An increased risk of bleeding Details Prasugrel Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Prasugrel Fondaparinux Arixtra Increased risk of bleeding Details Prasugrel Fondaparinux Injection Arixtra Increased risk of bleeding Details Prasugrel Heparin Increased risk of bleeding Details Prasugrel Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Prasugrel Ibrutinib Imbruvica Increased risk of bleeding Details Prasugrel Ibuprofen Addaprin An increased risk of bleeding Details Prasugrel Ketoprofen Actron® An increased risk of bleeding Details Prasugrel Ketorolac Acular An increased risk of bleeding Details Prasugrel Ketorolac Injection Acular An increased risk of bleeding Details Prasugrel Ketorolac Nasal Spray Sprix An increased risk of bleeding Details Prasugrel Ketorolac Ophthalmic Acular An increased risk of bleeding Details Prasugrel Meclofenamate Meclodium® An increased risk of bleeding Details Prasugrel Mefenamic Acid Ponstel® An increased risk of bleeding Details Prasugrel Meloxicam Alloxate An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.