Tetrabenazine

58 interactions 4 explained in plain English

Also sold as: Xenazine Xenazine®

About Tetrabenazine

Tetrabenazine is used to treat chorea (sudden movements that you cannot control) caused by Huntington's disease (an inherited disease that causes the progressive breakdown of nerve cells in the brain). Tetrabenazine is in a class of medications called vesicular monoamine transporter 2 (VMAT2) inhibitors. It works by ch… Read the full Tetrabenazine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Linezolid Injection Deutetrabenazine Sertraline Dasatinib Oxaliplatin Injection Amisulpride Injection

2 Contraindicated 56 Major

All (58) Contraindicated (2) Major (56)

Contraindicated

Tetrabenazine Deutetrabenazine Austedo Depletion of monoamines in the central nervous system Details Tetrabenazine Linezolid Injection Zyvox Elevated catecholamine levels Details

Major

Tetrabenazine Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Tetrabenazine Sertraline Explained Increased risk of QT interval prolongation and an increased CYP2D6 substrate exposure Details Tetrabenazine Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Tetrabenazine Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Tetrabenazine Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Tetrabenazine Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Tetrabenazine Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Tetrabenazine Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Tetrabenazine Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Tetrabenazine Azithromycin AzaSite An increased risk of QT interval prolongation Details Tetrabenazine Alfuzosin UroXatral An increased risk of QT interval prolongation Details Tetrabenazine Anagrelide Agrylin Increased risk of QT interval prolongation Details Tetrabenazine Bedaquiline Sirturo Increased risk of QT interval prolongation Details Tetrabenazine Chloroquine Aralen® An increased risk of QT interval prolongation Details Tetrabenazine Dasatinib Phyrago An increased risk of QT interval prolongation Details Tetrabenazine Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Tetrabenazine Disopyramide Norpace Increased risk of QT interval prolongation Details Tetrabenazine Dofetilide Tikosyn Increased risk of QT interval prolongation Details Tetrabenazine Dolasetron Anzemet An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Dolasetron Injection Anzemet An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Encorafenib Braftovi Increased risk of QT interval prolongation Details Tetrabenazine Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Tetrabenazine Flecainide Tambocor® An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Tetrabenazine Fostemsavir Rukobia Increased risk of torsade de pointes Details Tetrabenazine Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Gemifloxacin Factive An increased risk of QT interval prolongation Details Tetrabenazine Glasdegib Daurismo Increased risk of QT interval prolongation Details Tetrabenazine Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Tetrabenazine Granisetron Transdermal Patch Sancuso An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Granisetron Injection Granisol An increased risk of QT interval prolongation and torsade de pointes Details Tetrabenazine Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Tetrabenazine Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Tetrabenazine Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Tetrabenazine Ivabradine Corlanor Increased risk of QT prolongation Details Tetrabenazine Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Tetrabenazine Lefamulin Xenleta Increased risk of QT interval prolongation Details Tetrabenazine Lenvatinib Lenvima Increased risk of QT-interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.