Curcumin

22 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Loperamide Alpelisib Aspirin Fondaparinux Injection Heparin Dipyridamole
18 Major 4 Moderate
All (22) Major (18) Moderate (4)

Major

Curcumin Relugolix Orgovyx Explained Increased relugolix exposure Details Curcumin Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Curcumin Aspirin Acuprin® An increased risk of bleeding Details Curcumin Aspirin Rectal Aspirin An increased risk of bleeding Details Curcumin Betrixaban Bevyxxa® An increased risk of bleeding Details Curcumin Anagrelide Agrylin An increased risk of bleeding Details Curcumin Clopidogrel Plavix An increased risk of bleeding Details Curcumin Dalteparin Injection Fragmin An increased risk of bleeding Details Curcumin Digoxin Cardoxin® Altered digoxin exposure Details Curcumin Dipyridamole Permole® An increased risk of bleeding Details Curcumin Enoxaparin Lovenox An increased risk of bleeding Details Curcumin Enoxaparin Injection Lovenox An increased risk of bleeding Details Curcumin Everolimus Afinitor Decreased everolimus exposure Details Curcumin Fondaparinux Arixtra An increased risk of bleeding Details Curcumin Fondaparinux Injection Arixtra An increased risk of bleeding Details Curcumin Heparin An increased risk of bleeding Details Curcumin Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Curcumin Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details

Moderate

Curcumin Apixaban Eliquis Explained Increased exposure of apixaban and an increased risk of bleeding Details Curcumin Dabigatran Pradaxa® Increased exposure of dabigatran and an increased risk of bleeding Details Curcumin Dabigatran Etexilate Increased exposure of dabigatran and an increased risk of bleeding Details Curcumin Edoxaban Savaysa Increased exposure of edoxaban and an increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.