Metoclopramide Injection

247 interactions 689 cited references

Also sold as: Gimoti Metozolv Pileran Reglan Reglan® I.V.

About Metoclopramide Injection

Metoclopramide injection is used to relieve symptoms caused by slow stomach emptying in people who have diabetes. These symptoms include nausea, vomiting, heartburn, loss of appetite, and feeling of fullness that lasts long after meals. Metoclopramide injection is also used to prevent nausea and vomiting caused by chem… Read the full Metoclopramide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Fluvoxamine Haloperidol Iloperidone Imipramine Zuclopenthixol Loxapine

63 Contraindicated 174 Major 6 Moderate 4 Minor

All (247) Contraindicated (63) Major (174) Moderate (6) Minor (4)

Contraindicated

Metoclopramide Injection Amineptine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Amitriptyline Elavil An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Amitriptylinoxide An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Amoxapine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Aripiprazole Abilify An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Aripiprazole Lauroxil Aristada An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Asenapine Saphris An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Brexpiprazole Rexulti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Cariprazine Vraylar An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Chlorpromazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Chlorprothixene An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Citalopram Celexa An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Clomipramine Anafranil An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Clozapine Clozaril An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Desipramine Norpramin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Desvenlafaxine Pristiq An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Dibenzepin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Doxepin Prudoxin An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Duloxetine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Escitalopram Lexapro An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Fluphenazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Fluvoxamine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Haloperidol An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Iloperidone Fanapt An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Imipramine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Levomilnacipran An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Loxapine Adasuve An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Lurasidone Latuda An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Mavorixafor Xolremdi Increased CYP2D6 substrate exposure and an increased risk of CYP2D6 substrate-related adverse events Details Metoclopramide Injection Melitracen An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Mesoridazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Methotrimeprazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Milnacipran Savella An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Molindone An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Nefazodone An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Nortriptyline An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Olanzapine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Opipramol An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Paliperidone Erzofri An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Metoclopramide Injection Periciazine An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.