Granisetron Injection

281 interactions 403 cited references

Also sold as: Granisol Sancuso Sustol Sustol®

About Granisetron Injection

Granisetron immediate-release injection is used to prevent nausea and vomiting caused by cancer chemotherapy and to prevent and treat nausea and vomiting that may occur after surgery. Granisetron extended-release (long-acting) injection is used with other medications to prevent nausea and vomiting caused by cancer chem… Read the full Granisetron Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Phenelzine Pimozide Piperaquine Saquinavir Sparfloxacin Terfenadine

16 Contraindicated 265 Major

All (281) Contraindicated (16) Major (265)

Contraindicated

Granisetron Injection Apomorphine Apokyn Increased risk of profound hypotension and altered consciousness and an increased risk of QT interval prolongation, associated wit... Details Granisetron Injection Bepridil An increased risk of QT interval prolongation Details Granisetron Injection Cisapride Propulsid® Increased risk of QT interval prolongation Details Granisetron Injection Dronedarone Multaq Increased risk of QT interval prolongation Details Granisetron Injection Fluconazole Diflucan Increased granisetron exposure and an increased risk of QT interval prolongation Details Granisetron Injection Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Granisetron Injection Mesoridazine An increased risk of QT interval prolongation Details Granisetron Injection Phenelzine Nardil An increased risk of serotonin syndrome Details Granisetron Injection Pimozide An increased risk of QT interval prolongation Details Granisetron Injection Piperaquine An increased risk of QT interval prolongation Details Granisetron Injection Saquinavir An increased risk of QT interval prolongation Details Granisetron Injection Sparfloxacin An increased risk of QT interval prolongation Details Granisetron Injection Terfenadine An increased risk of QT interval prolongation Details Granisetron Injection Thioridazine An increased risk of QT interval prolongation Details Granisetron Injection Tranylcypromine Parnate An increased risk of serotonin syndrome Details Granisetron Injection Ziprasidone Geodon Increased risk of QT interval prolongation and an increased risk of serotonin syndrome (hypertension, hyperthermia, myoclonus, men... Details

Major

Granisetron Injection Adagrasib Krazati An increased risk of QT interval prolongation, torsade de pointes, polymorphic ventricular tachycardia, other serious arrhythmias Details Granisetron Injection Alfentanil Increased risk of serotonin syndrome Details Granisetron Injection Alfuzosin UroXatral An increased risk of QT interval prolongation Details Granisetron Injection Almotriptan Increased risk of serotonin syndrome Details Granisetron Injection Amineptine Increased risk of serotonin syndrome Details Granisetron Injection Amiodarone Nexterone An increased risk of QT interval prolongation and torsade de pointes Details Granisetron Injection Amisulpride Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Granisetron Injection Amitriptyline Elavil Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Injection Amitriptylinoxide Increased risk of serotonin syndrome Details Granisetron Injection Amoxapine Increased risk of serotonin syndrome and QT-interval prolongation Details Granisetron Injection Amphetamine Dexedrine An increased risk of serotonin syndrome Details Granisetron Injection Anagrelide Agrylin Increased risk of QT interval prolongation Details Granisetron Injection Anileridine Increased risk of serotonin syndrome Details Granisetron Injection Aripiprazole Abilify An increased risk of QT interval prolongation Details Granisetron Injection Aripiprazole Lauroxil Aristada An increased risk of QT interval prolongation Details Granisetron Injection Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Granisetron Injection Artemether An increased risk of QT interval prolongation Details Granisetron Injection Asenapine Saphris Increased risk of QT interval prolongation Details Granisetron Injection Astemizole An increased risk of QT interval prolongation Details Granisetron Injection Atazanavir Reyataz An increased risk of QT interval prolongation Details Granisetron Injection Azithromycin AzaSite An increased risk of QT interval prolongation Details Granisetron Injection Bedaquiline Sirturo Increased risk of QT interval prolongation Details Granisetron Injection Benzhydrocodone An increased risk of serotonin syndrome Details Granisetron Injection Benzphetamine An increased risk of serotonin syndrome Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.