Tenecteplase

23 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Lecanemab-Irmb Injection Enoxaparin Fondaparinux Edoxaban Heparin Injection
1 Contraindicated 17 Major 5 Moderate
All (23) Contraindicated (1) Major (17) Moderate (5)

Contraindicated

Tenecteplase Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Tenecteplase Apixaban Eliquis Explained An increased risk of bleeding Details Tenecteplase Betrixaban Bevyxxa® Increased risk of bleeding Details Tenecteplase Anagrelide Agrylin An increased risk of bleeding Details Tenecteplase Caplacizumab-Yhdp Injection Cablivi Increased risk of bleeding Details Tenecteplase Clopidogrel Plavix An increased risk of bleeding Details Tenecteplase Dabigatran Pradaxa® An increased risk of bleeding Details Tenecteplase Dabigatran Etexilate An increased risk of bleeding Details Tenecteplase Dalteparin Injection Fragmin An increased risk of bleeding Details Tenecteplase Dipyridamole Permole® An increased risk of bleeding Details Tenecteplase Edoxaban Savaysa An increased risk of bleeding Details Tenecteplase Enoxaparin Lovenox Increased risk of bleeding Details Tenecteplase Enoxaparin Injection Lovenox Increased risk of bleeding Details Tenecteplase Fondaparinux Arixtra An increased risk of bleeding Details Tenecteplase Fondaparinux Injection Arixtra An increased risk of bleeding Details Tenecteplase Heparin An increased risk of bleeding Details Tenecteplase Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Tenecteplase Lecanemab-Irmb Injection Leqembi An increased risk of amyloid related imaging abnormalities or intracerebral hemorrhage Details

Moderate

Tenecteplase Aspirin Acuprin® An increased risk of bleeding Details Tenecteplase Aspirin Rectal Aspirin An increased risk of bleeding Details Tenecteplase Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Tenecteplase Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details Tenecteplase Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.