Elafibranor

21 interactions 2 explained in plain English
Also sold as: Iqirvo
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Nifedipine Medroxyprogesterone Injection Estradiol Lovastatin Colestipol Levonorgestrel Intrauterine System
19 Major 2 Moderate
All (21) Major (19) Moderate (2)

Major

Elafibranor Simvastatin Flolipid Explained Increased risk of CPK elevation/myalgia and an increased risk of myopathy Details Elafibranor Atogepant Qulipta Reduced atogepant exposure Details Elafibranor Atorvastatin Atorvaliq Increased risk of CPK elevation/myalgia and an increased risk of myopathy Details Elafibranor Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Elafibranor Amlodipine Amvaz® Reduced amLODIPine exposure Details Elafibranor Cholestyramine Resin Locholest® Reduced elafibranor exposure and reduced efficacy of elafibranor Details Elafibranor Colesevelam Welchol Reduced elafibranor exposure and reduced efficacy of elafibranor Details Elafibranor Colestipol Colestid Reduced elafibranor exposure and reduced efficacy of elafibranor Details Elafibranor Estradiol Delestrogen Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Estradiol Topical Divigel Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Estradiol Transdermal Patch Alora® Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Fluvastatin Lescol Increased risk of CPK elevation/myalgia and an increased risk of myopathy Details Elafibranor Levonorgestrel After banger Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Levonorgestrel Intrauterine System Kyleena Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Lovastatin Altocor® Increased risk of CPK elevation/myalgia and an increased risk of myopathy Details Elafibranor Lumateperone Caplyta Reduced lumateperone exposure Details Elafibranor Medroxyprogesterone Amen® Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptives exposure, reduced efficacy of hormonal contraceptives and/or an increased risk of breakthrough ble... Details Elafibranor Nifedipine Adalat® Reduced NIFEdipine exposure Details

Moderate

Elafibranor Hydrocortisone Ala-Cort Reduced hydrocortisone exposure Details Elafibranor Hydrocortisone Injection A-Hydrocort® Reduced hydrocortisone exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.