Terbinafine

22 interactions 3 explained in plain English
Also sold as: Lamisil Lamisil® Silka Cream
About Terbinafine

Terbinafine is an antifungal medication used to treat fungal infections of the scalp, toenails, and fingernails. Read the full Terbinafine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Terbinafine Aripiprazole Injection Abilify Increased ARIPiprazole exposure Details Terbinafine Atogepant Qulipta Reduced atogepant exposure Details Terbinafine Azathioprine Azasan An increased risk of hepatotoxicity Details Terbinafine Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Terbinafine Amlodipine Amvaz® Reduced amLODIPine exposure Details Terbinafine Brexpiprazole Rexulti Increased brexpiprazole exposure Details Terbinafine Cyclosporine Injection Atopica Reduced cycloSPORINE exposure and a reduced therapeutic response to cycloSPORINE Details Terbinafine Cyclosporine Ophthalmic Cequa Reduced cycloSPORINE exposure and a reduced therapeutic response to cycloSPORINE Details Terbinafine Deutetrabenazine Austedo Increased deutetrabenazine exposure Details Terbinafine Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Terbinafine Lumateperone Caplyta Reduced lumateperone exposure Details Terbinafine Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Terbinafine Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Terbinafine Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Terbinafine Metoclopramide Injection Gimoti Increased metoclopramide exposure and risk of increased adverse events Details Terbinafine Metoclopramide Nasal Spray Gimoti Increased metoclopramide exposure and risk of increased adverse events Details Terbinafine Nebivolol Bystolic Increased exposure to nebivolol Details Terbinafine Nifedipine Adalat® Reduced NIFEdipine exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.