Bezafibrate

16 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Simvastatin Atorvastatin Cholestyramine Resin Colesevelam Colestipol
11 Major 5 Moderate
All (16) Major (11) Moderate (5)

Major

Bezafibrate Colchicine Colcrys Explained An increased risk of myopathy, including rhabdomyolysis Details Bezafibrate Simvastatin Flolipid Explained Increased incidence and severity of myopathy Details Bezafibrate Atorvastatin Atorvaliq Increased incidence and severity of myopathy Details Bezafibrate Cholestyramine Resin Locholest® Decreased bezafibrate efficacy Details Bezafibrate Colesevelam Welchol Decreased bezafibrate efficacy Details Bezafibrate Colestipol Colestid Decreased bezafibrate efficacy Details Bezafibrate Cyclosporine Injection Atopica Increased risk of renal dysfunction Details Bezafibrate Cyclosporine Ophthalmic Cequa Increased risk of renal dysfunction Details Bezafibrate Ezetimibe Zetia Increased ezetimibe exposure and an increased risk of cholelithiasis, myopathy and rhabdomyolysis Details Bezafibrate Fluvastatin Lescol Increased incidence and severity of myopathy Details Bezafibrate Lovastatin Altocor® Increased incidence and severity of myopathy Details

Moderate

Bezafibrate Bempedoic Acid Nexletol An increased triglycerides and reduced high-density lipoprotein cholesterol (HDL-C) Details Bezafibrate Glimepiride Amaryl Increased glimepiride exposure and increased blood glucose lowering effect and risk of hypoglycemia Details Bezafibrate Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Bezafibrate Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Bezafibrate Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.