Lenalidomide

16 interactions 346 cited references
Also sold as: Revlimid Revlimid®
About Lenalidomide

Lenalidomide is used to treat a certain type of myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Lenalidomide is also used along with dexamethasone to treat people with multiple myeloma (a type of cancer of… Read the full Lenalidomide drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 6 Major 1 Moderate
All (16) Contraindicated (9) Major (6) Moderate (1)

Contraindicated

Lenalidomide Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Lenalidomide Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Lenalidomide Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Lenalidomide Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Lenalidomide Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Lenalidomide Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Lenalidomide Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Lenalidomide Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

Moderate

Lenalidomide Digoxin Cardoxin® Increased digoxin plasma concentrations Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.