Estetrol

Major

Estetrol Amoxicillin Amoxi Drop Reduced efficacy of oral contraceptive Details Estetrol Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Estetrol Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Estetrol Dexamethasone Injection Decadron Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive, increased risk of breakthrough bleeding and/o... Details Estetrol Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptive, increased risk of breakthrough bleeding and/o... Details Estetrol Doxycycline Injection Acticlate Reduced efficacy of oral contraceptive Details Estetrol Enasidenib Idhifa Reduced hormonal contraceptive exposure and reduced efficacy of hormonal contraceptive and an increased risk of breakthrough bleed... Details Estetrol Encorafenib Braftovi Reduced hormonal contraceptives exposure and reduced efficacy of hormonal contraceptives Details Estetrol Exenatide Injection Bydureon Reduced oral contraceptives absorption and reduced efficacy of oral contraceptives Details Estetrol Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Estetrol Hydrocortisone Ala-Cort Altered (reduced/increased) hydrocortisone exposure, reduced efficacy of hydrocortisone and an increased risk of hydrocortisone-re... Details Estetrol Hydrocortisone Injection A-Hydrocort® Altered (reduced/increased) hydrocortisone exposure, reduced efficacy of hydrocortisone and an increased risk of hydrocortisone-re... Details Estetrol Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Estetrol Meropenem Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Estetrol Meropenem Injection Merrem® Reduced hormonal contraceptive exposure and an increased risk of contraceptive failure Details Estetrol Methylergonovine Methergine Increased methylergonovine exposure Details Estetrol Mitapivat Aqvesme Reduced hormonal contraceptive exposure Details Estetrol Nafcillin Injection Unipen® Injection Reduced hormonal contraceptive exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Estetrol Nevirapine Viramune Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and increased risk of breakthrough bleeding a... Details Estetrol Nifedipine Adalat® Increased NIFEdipine exposure Details

Moderate

Estetrol Cholestyramine Resin Locholest® Decreased estetrol and drospirenone exposure Details Estetrol Clopidogrel Plavix Reduced clopidogrel active metabolite exposure and reduced platelet inhibition Details Estetrol Colesevelam Welchol Decreased estetrol and drospirenone exposure Details Estetrol Colestipol Colestid Decreased estetrol and drospirenone exposure Details Estetrol Dofetilide Tikosyn Increased dofetilide exposure Details Estetrol Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details